Amaryl and Bradyarrhythmia - a phase IV clinical study of FDA data

Summary:

Bradyarrhythmia is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Cardiac failure.

The phase IV clinical study analyzes which people have Bradyarrhythmia when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Bradyarrhythmia?

Bradyarrhythmia (heart slowness) is found to be associated with 276 drugs and 350 conditions by eHealthMe. Check the latest studies of Bradyarrhythmia.



On Jul, 10, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 23 people (0.07%) have Bradyarrhythmia.

Could Amaryl cause Bradyarrhythmia?

Among these 23 people:

How long have people been on Amaryl when they have Bradyarrhythmia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bradyarrhythmia when taking Amaryl? *

  • female: 72.73 %
  • male: 27.27 %

What is the age of people who have Bradyarrhythmia when taking Amaryl? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5 %
  • 30-39: 0.0 %
  • 40-49: 5 %
  • 50-59: 0.0 %
  • 60+: 90 %

What are other drugs people take besides Amaryl? *

  1. Aspirin: 7 people, 30.43%
  2. Lisinopril: 6 people, 26.09%
  3. Zetia: 4 people, 17.39%
  4. Ramipril: 4 people, 17.39%
  5. Coumadin: 4 people, 17.39%
  6. Lasix: 4 people, 17.39%
  7. Digoxin: 4 people, 17.39%
  8. Plavix: 4 people, 17.39%
  9. Leuprolide Acetate: 3 people, 13.04%
  10. Prednisone: 3 people, 13.04%

What are other side effects people have besides Bradyarrhythmia? *

  1. Fainting (loss of consciousness and postural tone): 7 people, 30.43%
  2. Dyspnea (difficult or laboured breathing): 6 people, 26.09%
  3. Hypotension (abnormally low blood pressure): 6 people, 26.09%
  4. Enlarged Heart: 6 people, 26.09%
  5. Chest Pain: 6 people, 26.09%
  6. Pulmonary Congestion (congestion in the lungs): 6 people, 26.09%
  7. Hyperkalemia (damage to or disease of the kidney): 5 people, 21.74%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 21.74%
  9. Pleural Effusion (water on the lungs): 5 people, 21.74%
  10. Sick Sinus Syndrome (a collection of heart rhythm disorders): 4 people, 17.39%

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 8.70%
  2. Cardiac Failure: 2 people, 8.70%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.35%
  4. Hypertensive Heart Disease: 1 person, 4.35%
  5. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 4.35%
  6. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 4.35%
  7. Cardiac Failure Congestive: 1 person, 4.35%
  8. Acute Myocardial Infarction (acute heart attack): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Bradyarrhythmia?

- Check whether Bradyarrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Bradyarrhythmia treatments and more:

How severe was Bradyarrhythmia and when was it recovered:

Expand to all the drugs that have ingredients of glimepiride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradyarrhythmia:

Browse all the conditions that are associated with Bradyarrhythmia:


How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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