Leflunomide and Nervous system disorder - a phase IV clinical study of FDA data

Summary:

Nervous system disorder is reported as a side effect among people who take Leflunomide (leflunomide), especially for people who are female, 10-19 old, have been taking the drug for 2 - 5 years also take Enbrel, and have Juvenile rheumatoid arthritis.

The phase IV clinical study analyzes which people have Nervous system disorder when taking Leflunomide. It is created by eHealthMe based on reports of 81,713 people who have side effects when taking Leflunomide from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Nervous system disorder?

Nervous system disorder (a general class of medical conditions affecting the nervous system) is found to be associated with 1,360 drugs and 1,689 conditions by eHealthMe. Check the latest studies of Nervous system disorder.

On Jul, 10, 2026

81,713 people reported to have side effects when taking Leflunomide.
Among them, 104 people (0.13%) have Nervous system disorder.

Could Leflunomide cause Nervous system disorder?

Among these 104 people:

How long have people been on Leflunomide when they have Nervous system disorder? *

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What is the gender of people who have Nervous system disorder when taking Leflunomide? *

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What is the age of people who have Nervous system disorder when taking Leflunomide? *

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* Approximation only. Some reports may have incomplete information.

Do you take Leflunomide and have Nervous system disorder?

- Check whether Nervous system disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leflunomide:

Leflunomide (82,105 reports)

Nervous system disorder treatments and more:

Nervous system disorder (39,575 reports)

How severe was Nervous system disorder and when was it recovered:

Nervous system disorder in Leflunomide

Expand to all the drugs that have ingredients of leflunomide:

Nervous system disorder and drugs with ingredients of leflunomide

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Leflunomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nervous system disorder:

Nervous system disorder (1,360 drugs)

Browse all the conditions that are associated with Nervous system disorder:

Nervous system disorder (1,689 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide (the active ingredients of Leflunomide) and Leflunomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.