Amaryl and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are female, 60+ old, also take Diovan, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 680 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 15, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 27 people (0.08%) have Diastolic dysfunction.

Could Amaryl cause Diastolic dysfunction?

Among these 27 people:

What is the gender of people who have Diastolic dysfunction when taking Amaryl? *

female: 70.37 %
male: 29.63 %

What is the age of people who have Diastolic dysfunction when taking Amaryl? *

What are other drugs people take besides Amaryl? *

What are other side effects people have besides Diastolic dysfunction? *

Cardiac Failure Congestive: 13 people, 48.15%
Acute Kidney Failure: 10 people, 37.04%
Fall: 8 people, 29.63%
Fever: 8 people, 29.63%
Urinary Tract Infection: 8 people, 29.63%
Pressure Ulcer: 7 people, 25.93%
Chest Pain: 7 people, 25.93%
Cardiac Disorder: 7 people, 25.93%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 25.93%
Dyspnea (difficult or laboured breathing): 6 people, 22.22%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 22.22%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 14.81%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 11.11%
Pain In Extremity: 2 people, 7.41%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 7.41%
Depression: 2 people, 7.41%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.70%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.70%
High Blood Pressure: 1 person, 3.70%
Cardiomyopathy (weakening of the heart muscle): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Amaryl (32,259 reports)

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (680 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.