Amaryl and Dysphoria - a phase IV clinical study of FDA data

Summary:

Dysphoria is reported as a side effect among people who take Amaryl (glimepiride), especially for people who are male, 50-59 old, also take Lasix, and have Autism spectrum disorder.

The phase IV clinical study analyzes which people have Dysphoria when taking Amaryl. It is created by eHealthMe based on reports of 31,980 people who have side effects when taking Amaryl from the FDA, and is updated regularly.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

What is Dysphoria?

Dysphoria (generalized dissatisfaction with life) is found to be associated with 352 drugs and 534 conditions by eHealthMe. Check the latest studies of Dysphoria.

On Jul, 14, 2026

31,980 people reported to have side effects when taking Amaryl.
Among them, 13 people (0.04%) have Dysphoria.

Among these 13 people:

What is the gender of people who have Dysphoria when taking Amaryl? *

female: 8.33 %
male: 91.67 %

What is the age of people who have Dysphoria when taking Amaryl? *

What are other drugs people take besides Amaryl? *

What are other side effects people have besides Dysphoria? *

Nausea (feeling of having an urge to vomit): 6 people, 46.15%
Upper Gastrointestinal Haemorrhage (upper gastrointestinal bleeding): 6 people, 46.15%
Stress And Anxiety: 6 people, 46.15%
Dyspnea (difficult or laboured breathing): 5 people, 38.46%
Headache (pain in head): 5 people, 38.46%
Depressed Level Of Consciousness: 5 people, 38.46%
Fever: 5 people, 38.46%
Liver Disorder (liver diseases): 4 people, 30.77%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 30.77%
Hyperhidrosis (abnormally increased sweating): 4 people, 30.77%

What are the existing conditions these people have? *

Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 3 people, 23.08%
Neuralgia (pain in one or more nerves): 2 people, 15.38%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 7.69%
Prostate Cancer: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Amaryl and have Dysphoria?

- Check whether Dysphoria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amaryl:

Amaryl (32,259 reports)

Dysphoria treatments and more:

Dysphoria (5,565 reports)

Browse all side effects of Amaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysphoria:

Dysphoria (352 drugs)

Browse all the conditions that are associated with Dysphoria:

Dysphoria (534 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Amaryl) and Amaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.