Ambien cr and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Ambien cr (zolpidem tartrate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Lipitor, and have Depression.

The phase IV clinical study analyzes which people have Heart attack when taking Ambien cr. It is created by eHealthMe based on reports of 4,630 people who have side effects when taking Ambien cr from the FDA, and is updated regularly.

What is Ambien cr?

Ambien cr has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 5,660 Ambien cr users. Check the latest studies of Ambien cr.

What is Heart attack?

Heart attack is found to be associated with 2,475 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

4,630 people reported to have side effects when taking Ambien cr.
Among them, 36 people (0.78%) have Heart attack.

Could Ambien cr cause Heart attack?

Among these 36 people:

How long have people been on Ambien cr when they have Heart attack? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart attack when taking Ambien cr? *

  • female: 38.89 %
  • male: 61.11 %

What is the age of people who have Heart attack when taking Ambien cr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.38 %
  • 40-49: 21.88 %
  • 50-59: 21.88 %
  • 60+: 46.88 %

What are other drugs people take besides Ambien cr? *

  1. Lipitor: 9 people, 25.00%
  2. Abilify: 6 people, 16.67%
  3. Percocet: 6 people, 16.67%
  4. Flexeril: 5 people, 13.89%
  5. Lyrica: 5 people, 13.89%
  6. Ibuprofen: 5 people, 13.89%
  7. Nucynta: 4 people, 11.11%
  8. Methotrexate: 4 people, 11.11%
  9. Seroquel: 4 people, 11.11%
  10. Synthroid: 4 people, 11.11%

What are other side effects people have besides Heart attack? *

  1. Fatigue (feeling of tiredness): 9 people, 25.00%
  2. Joint Pain: 7 people, 19.44%
  3. Pneumonia: 6 people, 16.67%
  4. Hypotension (abnormally low blood pressure): 5 people, 13.89%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.89%
  6. Dyspnea (difficult or laboured breathing): 5 people, 13.89%
  7. Depression: 5 people, 13.89%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 13.89%
  9. Nausea (feeling of having an urge to vomit): 5 people, 13.89%
  10. Constipation: 4 people, 11.11%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 16.67%
  2. Depression: 6 people, 16.67%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 13.89%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 13.89%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 13.89%
  6. Back Pain: 4 people, 11.11%
  7. Hiv Infection: 3 people, 8.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.33%
  9. Pain: 3 people, 8.33%
  10. High Blood Cholesterol: 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien cr and have Heart attack?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien cr:

Heart attack treatments and more:

How severe was Heart attack and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Browse all the conditions that are associated with Heart attack:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien cr) and Ambien cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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