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Ambien and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are female, 60+ old, also take Coumadin, and have Pain.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,512 Ambien users. Check the latest studies of Ambien.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,237 drugs and 836 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Dec, 02, 2025

86,763 people reported to have side effects when taking Ambien.
Among them, 89 people (0.1%) have Sinus node dysfunction.

Could Ambien cause Sinus node dysfunction?

Among these 89 people:

What is the gender of people who have Sinus node dysfunction when taking Ambien? *

  • female: 59.77 %
  • male: 40.23 %

What is the age of people who have Sinus node dysfunction when taking Ambien? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.3 %
  • 40-49: 12.99 %
  • 50-59: 3.9 %
  • 60+: 81.82 %

What are other drugs people take besides Ambien? *

  1. Coumadin: 45 people, 50.56%
  2. Toprol-Xl: 41 people, 46.07%
  3. Zometa: 37 people, 41.57%
  4. Albuterol: 33 people, 37.08%
  5. Klor-Con: 31 people, 34.83%
  6. Lanoxin: 30 people, 33.71%
  7. Morphine: 30 people, 33.71%
  8. Thalomid: 30 people, 33.71%
  9. Amoxicillin: 30 people, 33.71%
  10. Xanax: 29 people, 32.58%

What are other side effects people have besides Sinus node dysfunction? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 66 people, 74.16%
  2. Weakness: 48 people, 53.93%
  3. Dizziness: 47 people, 52.81%
  4. Stress And Anxiety: 47 people, 52.81%
  5. Pain: 46 people, 51.69%
  6. Cardiac Failure Congestive: 43 people, 48.31%
  7. High Blood Pressure: 42 people, 47.19%
  8. Injury: 40 people, 44.94%
  9. Fatigue (feeling of tiredness): 40 people, 44.94%
  10. Anaemia (lack of blood): 36 people, 40.45%

What are the existing conditions these people have? *

  1. Pain: 24 people, 26.97%
  2. Metastases To Bone (cancer spreads to bone): 16 people, 17.98%
  3. Depression: 13 people, 14.61%
  4. Constipation: 11 people, 12.36%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 8.99%
  6. Stress And Anxiety: 6 people, 6.74%
  7. Nervousness: 6 people, 6.74%
  8. Non-Hodgkin's Lymphoma Stage Iii (malignant (cancer) cells form in the lymph system- stage iii): 5 people, 5.62%
  9. Prothrombin Level Abnormal: 5 people, 5.62%
  10. Diabetes: 4 people, 4.49%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Sinus node dysfunction treatments and more:

How severe was Sinus node dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Browse all the conditions that are associated with Sinus node dysfunction:

Drugs similar to Ambien and Sinus node dysfunction :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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