Ambrisentan and Heart valve surgery - a phase IV clinical study of FDA data

Summary:

Heart valve surgery is reported as a side effect among people who take Ambrisentan (ambrisentan), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Adcirca, and have Pulmonary hypertension.

The phase IV clinical study analyzes which people have Heart valve surgery when taking Ambrisentan. It is created by eHealthMe based on reports of 61,294 people who have side effects when taking Ambrisentan from the FDA, and is updated regularly.

What is Ambrisentan?

Ambrisentan has active ingredients of ambrisentan. eHealthMe is studying from 61,368 Ambrisentan users. Check the latest studies of Ambrisentan.

What is Heart valve surgery?

Heart valve surgery is found to be associated with 151 drugs and 437 conditions by eHealthMe. Check the latest studies of Heart valve surgery.

On Jul, 16, 2026

61,294 people reported to have side effects when taking Ambrisentan.
Among them, 52 people (0.08%) have Heart valve surgery.

Could Ambrisentan cause Heart valve surgery?

Among these 52 people:

How long have people been on Ambrisentan when they have Heart valve surgery? *

What is the gender of people who have Heart valve surgery when taking Ambrisentan? *

female: 73.08 %
male: 26.92 %

What is the age of people who have Heart valve surgery when taking Ambrisentan? *

What are other drugs people take besides Ambrisentan? *

What are other side effects people have besides Heart valve surgery? *

Dyspnea (difficult or laboured breathing): 5 people, 9.62%
Cardiac Disorder: 4 people, 7.69%
Weight Decreased: 3 people, 5.77%
Dizziness: 3 people, 5.77%
Ill-Defined Disorder: 2 people, 3.85%
Arthropathy: 2 people, 3.85%
Cardiac Failure Congestive: 2 people, 3.85%
Diarrhea: 2 people, 3.85%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 3.85%
Haemoglobin Decreased: 2 people, 3.85%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 17 people, 32.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 17.31%
Tricuspid Valve Disease (disease of heart valve): 1 person, 1.92%
Transposition Of The Great Vessels: 1 person, 1.92%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 1.92%
Pulmonary Valve Stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve): 1 person, 1.92%
Mitral Valve Stenosis (narrowing of mitral valve): 1 person, 1.92%
Hiv Infection: 1 person, 1.92%
Atherosclerosis (disorder of the arteries): 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Ambrisentan and have Heart valve surgery?

- Check whether Heart valve surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambrisentan:

Ambrisentan (61,368 reports)

Browse all side effects of Ambrisentan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart valve surgery:

Heart valve surgery (151 drugs)

Browse all the conditions that are associated with Heart valve surgery:

Heart valve surgery (437 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ambrisentan (the active ingredients of Ambrisentan) and Ambrisentan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.