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Amiodarone hydrochloride and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Amiodarone hydrochloride (amiodarone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Buspirone Hydrochloride, and have Pain.

The phase IV clinical study analyzes which people have Mental status changes when taking Amiodarone hydrochloride. It is created by eHealthMe based on reports of 9,284 people who have side effects when taking Amiodarone hydrochloride from the FDA, and is updated regularly.

What is Amiodarone hydrochloride?

Amiodarone hydrochloride has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 10,061 Amiodarone hydrochloride users. Check the latest studies of Amiodarone hydrochloride.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,497 drugs and 1,759 conditions by eHealthMe. Check the latest studies of Mental status changes.

On Jul, 22, 2026

9,284 people reported to have side effects when taking Amiodarone hydrochloride.
Among them, 31 people (0.33%) have Mental status changes.

Could Amiodarone hydrochloride cause Mental status changes?

Among these 31 people:

How long have people been on Amiodarone hydrochloride when they have Mental status changes? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mental status changes when taking Amiodarone hydrochloride? *

  • female: 48.39 %
  • male: 51.61 %

What is the age of people who have Mental status changes when taking Amiodarone hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.7 %
  • 40-49: 7.41 %
  • 50-59: 3.7 %
  • 60+: 85.19 %

What are other drugs people take besides Amiodarone hydrochloride? *

  1. Lexapro: 6 people, 19.35%
  2. Toprol-Xl: 6 people, 19.35%
  3. Lisinopril: 6 people, 19.35%
  4. Novolog: 6 people, 19.35%
  5. Propofol: 6 people, 19.35%
  6. Buspirone Hydrochloride: 6 people, 19.35%
  7. Flagyl: 5 people, 16.13%
  8. Levaquin: 5 people, 16.13%
  9. Ancef: 5 people, 16.13%
  10. Pantoprazole: 4 people, 12.90%

What are other side effects people have besides Mental status changes? *

  1. Fatigue (feeling of tiredness): 11 people, 35.48%
  2. Hypotension (abnormally low blood pressure): 11 people, 35.48%
  3. Unresponsive To Stimuli: 10 people, 32.26%
  4. Dyspnea (difficult or laboured breathing): 10 people, 32.26%
  5. Nausea (feeling of having an urge to vomit): 9 people, 29.03%
  6. Nausea And Vomiting: 8 people, 25.81%
  7. Respiratory Distress (difficulty in breathing): 8 people, 25.81%
  8. Dementia (madness): 6 people, 19.35%
  9. Diarrhea: 6 people, 19.35%
  10. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 6 people, 19.35%

What are the existing conditions these people have? *

  1. Pain: 4 people, 12.90%
  2. Itching: 3 people, 9.68%
  3. Anaemia (lack of blood): 3 people, 9.68%
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 6.45%
  5. Viral Skin Infection: 2 people, 6.45%
  6. Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 2 people, 6.45%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 6.45%
  8. Diabetes: 2 people, 6.45%
  9. Autoimmune Hepatitis: 2 people, 6.45%
  10. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Amiodarone hydrochloride and have Mental status changes?

- Check whether Mental status changes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amiodarone hydrochloride:

Mental status changes treatments and more:

How severe was Mental status changes and when was it recovered:

Expand to all the drugs that have ingredients of amiodarone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amiodarone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Browse all the conditions that are associated with Mental status changes:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride (the active ingredients of Amiodarone hydrochloride) and Amiodarone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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