Amitiza and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Amitiza (lubiprostone), especially for people who are female, 60+ old, also take Synthroid, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Amitiza. It is created by eHealthMe based on reports of 10,225 people who have side effects when taking Amitiza from the FDA, and is updated regularly.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,682 drugs and 1,587 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Nov, 10, 2025

10,225 people reported to have side effects when taking Amitiza.
Among them, 31 people (0.3%) have Thyroid function test abnormal.

Could Amitiza cause Thyroid function test abnormal?

Among these 31 people:

What is the gender of people who have Thyroid function test abnormal when taking Amitiza? *

female: 75.86 %
male: 24.14 %

What is the age of people who have Thyroid function test abnormal when taking Amitiza? *

What are other drugs people take besides Amitiza? *

What are other side effects people have besides Thyroid function test abnormal? *

Rashes (redness): 7 people, 22.58%
Neuralgia (pain in one or more nerves): 7 people, 22.58%
High Blood Pressure: 6 people, 19.35%
Insomnia (sleeplessness): 6 people, 19.35%
Dyspnea (difficult or laboured breathing): 6 people, 19.35%
Drug Ineffective: 6 people, 19.35%
Weight Decreased: 5 people, 16.13%
Pain In Extremity: 5 people, 16.13%
Depression: 5 people, 16.13%
Fatigue (feeling of tiredness): 5 people, 16.13%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.13%
Migraine (headache): 5 people, 16.13%
Asthma: 4 people, 12.90%
Joint Pain: 4 people, 12.90%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 12.90%
Nausea (feeling of having an urge to vomit): 4 people, 12.90%
High Blood Pressure: 4 people, 12.90%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 9.68%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Amitiza and have Thyroid function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amitiza:

Amitiza (10,567 reports)

Browse all side effects of Amitiza:

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Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,682 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,587 conditions)

Drugs similar to Amitiza and Thyroid function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on lubiprostone (the active ingredients of Amitiza) and Amitiza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.