Amitriptyline hydrochloride and Breast cancer - a phase IV clinical study of FDA data

Summary:

Breast cancer is reported as a side effect among people who take Amitriptyline hydrochloride (amitriptyline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Premarin, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Breast cancer when taking Amitriptyline hydrochloride. It is created by eHealthMe based on reports of 16,582 people who have side effects when taking Amitriptyline hydrochloride from the FDA, and is updated regularly.

What is Amitriptyline hydrochloride?

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.

What is Breast cancer?

Breast cancer is found to be associated with 1,296 drugs and 1,668 conditions by eHealthMe. Check the latest studies of Breast cancer.

On Jul, 24, 2026

16,582 people reported to have side effects when taking Amitriptyline hydrochloride.
Among them, 38 people (0.23%) have Breast cancer.

Could Amitriptyline hydrochloride cause Breast cancer?

Among these 38 people:

How long have people been on Amitriptyline hydrochloride when they have Breast cancer? *

What is the gender of people who have Breast cancer when taking Amitriptyline hydrochloride? *

female: 97.14 %
male: 2.86 %

What is the age of people who have Breast cancer when taking Amitriptyline hydrochloride? *

What are other drugs people take besides Amitriptyline hydrochloride? *

What are other side effects people have besides Breast cancer? *

Nausea (feeling of having an urge to vomit): 5 people, 13.16%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 10.53%
Diarrhea: 4 people, 10.53%
Fever: 4 people, 10.53%
Abdominal Discomfort: 3 people, 7.89%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 7.89%
Joint Pain: 3 people, 7.89%
Weight Decreased: 3 people, 7.89%
Anaemia (lack of blood): 3 people, 7.89%
Arrhythmias (irregular heartbeat): 2 people, 5.26%

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 10.53%
Back Pain: 3 people, 7.89%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.89%
Abdominal Pain Upper: 2 people, 5.26%
Arrhythmias (irregular heartbeat): 2 people, 5.26%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 5.26%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.26%
Parkinson's Disease: 2 people, 5.26%
Osteoporosis (bones weak and more likely to break): 2 people, 5.26%
Stress And Anxiety: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Amitriptyline hydrochloride and have Breast cancer?

- Check whether Breast cancer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amitriptyline hydrochloride:

Amitriptyline hydrochloride (20,054 reports)

Breast cancer treatments and more:

Breast cancer (266,434 reports)

Browse all side effects of Amitriptyline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Breast cancer:

Breast cancer (1,296 drugs)

Browse all the conditions that are associated with Breast cancer:

Breast cancer (1,668 conditions)

Related publications that referenced our studies

Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride (the active ingredients of Amitriptyline hydrochloride) and Amitriptyline hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.