Amlodipine besylate and Macroglossia - a phase IV clinical study of FDA data

Summary:

Macroglossia is reported as a side effect among people who take Amlodipine besylate (amlodipine besylate), especially for people who are male, 60+ old, also take Hydrocortisone Sodium Succinate, and have Depression.

The phase IV clinical study analyzes which people have Macroglossia when taking Amlodipine besylate. It is created by eHealthMe based on reports of 71,608 people who have side effects when taking Amlodipine besylate from the FDA, and is updated regularly.

What is Amlodipine besylate?

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 75,293 Amlodipine besylate users. Check the latest studies of Amlodipine besylate.

What is Macroglossia?

Macroglossia (large tongue) is found to be associated with 117 drugs and 38 conditions by eHealthMe. Check the latest studies of Macroglossia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

71,608 people reported to have side effects when taking Amlodipine besylate.
Among them, 11 people (0.02%) have Macroglossia.

Could Amlodipine besylate cause Macroglossia?

Among these 11 people:

What is the gender of people who have Macroglossia when taking Amlodipine besylate? *

female: 30 %
male: 70 %

What is the age of people who have Macroglossia when taking Amlodipine besylate? *

What are other drugs people take besides Amlodipine besylate? *

Epinephrine: 2 people, 18.18%
Atorvastatin Calcium: 2 people, 18.18%
Icatibant Acetate: 2 people, 18.18%
Carvedilol: 2 people, 18.18%
Lysine Acetylsalicylate: 2 people, 18.18%
Hydrocortisone Sodium Succinate: 2 people, 18.18%
Zolpidem Tartrate: 1 person, 9.09%
Fluconazole: 1 person, 9.09%
Fentanyl: 1 person, 9.09%
Famotidine: 1 person, 9.09%

What are other side effects people have besides Macroglossia? *

Angioedema (rapid swelling of the dermis): 8 people, 72.73%
Swelling Face: 3 people, 27.27%
Speech Impairment (Adult) (inability to speak (adult)): 2 people, 18.18%
Oedema Peripheral (superficial swelling): 2 people, 18.18%
Drug Ineffective: 2 people, 18.18%
Tongue Oedema (swelling of tongue): 2 people, 18.18%
Upper Airway Obstruction: 1 person, 9.09%
Generalised Erythema (redness of the skin all over the body): 1 person, 9.09%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 9.09%
Angioneurotic Oedema (swelling that occurs just beneath the surface of the skin or mucous membranes): 1 person, 9.09%

What are the existing conditions these people have? *

Hallucinations (sensations that appear real but are created by your mind): 1 person, 9.09%
Depression: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine besylate and have Macroglossia?

- Check whether Macroglossia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine besylate:

Amlodipine besylate (75,293 reports)

Macroglossia treatments and more:

Macroglossia (665 reports)

Browse all side effects of Amlodipine besylate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macroglossia:

Macroglossia (117 drugs)

Browse all the conditions that are associated with Macroglossia:

Macroglossia (38 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine besylate) and Amlodipine besylate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.