Amlodipine and Accidental death - a phase IV clinical study of FDA data

Summary:

Accidental death is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are male, 60+ old, also take Alprazolam, and have Depression.

The study is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

On Jul, 12, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 13 people (0.0%) died.

Could Amlodipine cause Accidental death?

Among these 13 people:

What is the gender of people who died when taking Amlodipine? *

female: 9.09 %
male: 90.91 %

What is the age of people who died when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have before they died? *

Fall: 4 people, 30.77%
Fungal Nail Infection: 2 people, 15.38%
Injury: 2 people, 15.38%
Implant Site Infection: 2 people, 15.38%
Implant Site Extravasation: 2 people, 15.38%
Hypotonia (low muscle tone): 2 people, 15.38%
Hepatic Steatosis (fatty liver disease): 2 people, 15.38%
Haemorrhage Intracranial (bleeding within the skull): 2 people, 15.38%
Gamma-Glutamyltransferase Abnormal: 2 people, 15.38%
Wound Infection: 2 people, 15.38%

What are the existing conditions these people have? *

Depression: 4 people, 30.77%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 15.38%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 15.38%
Oedema Peripheral (superficial swelling): 2 people, 15.38%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 15.38%
Insomnia (sleeplessness): 2 people, 15.38%
Erection Problems: 2 people, 15.38%
Diabetes: 2 people, 15.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 15.38%
Cardiac Disorder: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,829 reports)

Expand to all the drugs that have ingredients of amlodipine besylate:

Accidental death and drugs with ingredients of amlodipine besylate (15 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Accidental death:

Accidental death (147 drugs)

Browse all the conditions that are associated with Accidental death:

Accidental death (170 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.