Amlodipine and Application site irritation - a phase IV clinical study of FDA data

Summary:

Application site irritation is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, also take Veletri, and have Hair loss.

The phase IV clinical study analyzes which people have Application site irritation when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Application site irritation?

Application site irritation is found to be associated with 391 drugs and 697 conditions by eHealthMe. Check the latest studies of Application site irritation.

On Jul, 10, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 74 people (0.02%) have Application site irritation.

Could Amlodipine cause Application site irritation?

Among these 74 people:

What is the gender of people who have Application site irritation when taking Amlodipine? *

female: 60.56 %
male: 39.44 %

What is the age of people who have Application site irritation when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have besides Application site irritation? *

Application Site Erythema (redness of the skin at application site): 31 people, 41.89%
Application Site Pruritus (application site severe itching of the skin): 29 people, 39.19%
Application Site Pain: 16 people, 21.62%
Drug Ineffective: 9 people, 12.16%
Rashes (redness): 8 people, 10.81%
Application Site Rash: 8 people, 10.81%
Headache (pain in head): 7 people, 9.46%
Pain: 7 people, 9.46%
Pain In Extremity: 7 people, 9.46%
Pain In Jaw: 7 people, 9.46%

What are the existing conditions these people have? *

Hair Loss: 15 people, 20.27%
High Blood Cholesterol: 12 people, 16.22%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 5.41%
Diabetes: 4 people, 5.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.41%
Back Pain: 3 people, 4.05%
Pain: 3 people, 4.05%
Stress And Anxiety: 3 people, 4.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 4.05%
Blood Testosterone Decreased: 3 people, 4.05%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Application site irritation?

- Check whether Application site irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,829 reports)

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site irritation:

Application site irritation (391 drugs)

Browse all the conditions that are associated with Application site irritation:

Application site irritation (697 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.