Amlodipine and Application site vesicles - a phase IV clinical study of FDA data

Summary:

Application site vesicles is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, also take Butrans, and have Pain.

The phase IV clinical study analyzes which people have Application site vesicles when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Application site vesicles?

Application site vesicles (small bubble within a cell at application site) is found to be associated with 273 drugs and 570 conditions by eHealthMe. Check the latest studies of Application site vesicles.

On Jul, 12, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 54 people (0.02%) have Application site vesicles.

Could Amlodipine cause Application site vesicles?

Among these 54 people:

What is the gender of people who have Application site vesicles when taking Amlodipine? *

female: 63.46 %
male: 36.54 %

What is the age of people who have Application site vesicles when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have besides Application site vesicles? *

Application Site Pruritus (application site severe itching of the skin): 20 people, 37.04%
Application Site Pain: 14 people, 25.93%
Application Site Rash: 12 people, 22.22%
Application Site Erythema (redness of the skin at application site): 10 people, 18.52%
Application Site Discoloration: 7 people, 12.96%
Rashes (redness): 7 people, 12.96%
Itching: 7 people, 12.96%
Drug Ineffective: 6 people, 11.11%
Application Site Swelling: 5 people, 9.26%
Application Site Discharge: 5 people, 9.26%

What are the existing conditions these people have? *

Pain: 9 people, 16.67%
High Blood Cholesterol: 5 people, 9.26%
Athlete's Foot (a fungal infection affecting the skin between the toes): 4 people, 7.41%
Actinic Keratosis (skin disease due to sun exposure): 4 people, 7.41%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 5.56%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 3 people, 5.56%
Blood Testosterone Decreased: 3 people, 5.56%
Back Pain: 3 people, 5.56%
Hair Loss: 3 people, 5.56%
Sleep Disorder: 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Application site vesicles?

- Check whether Application site vesicles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,829 reports)

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site vesicles:

Application site vesicles (273 drugs)

Browse all the conditions that are associated with Application site vesicles:

Application site vesicles (570 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.