Amlodipine and Gingival hyperplasia - a phase IV clinical study of FDA data

Summary:

Gingival hyperplasia is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Ramipril, and have Dry skin.

The phase IV clinical study analyzes which people have Gingival hyperplasia when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,833 Amlodipine users. Check the latest studies of Amlodipine.

What is Gingival hyperplasia?

Gingival hyperplasia (overgrowth of gums) is found to be associated with 154 drugs and 263 conditions by eHealthMe. Check the latest studies of Gingival hyperplasia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 152 people (0.04%) have Gingival hyperplasia.

Could Amlodipine cause Gingival hyperplasia?

Among these 152 people:

How long have people been on Amlodipine when they have Gingival hyperplasia? *

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What is the gender of people who have Gingival hyperplasia when taking Amlodipine? *

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What is the age of people who have Gingival hyperplasia when taking Amlodipine? *

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* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Gingival hyperplasia?

- Check whether Gingival hyperplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,833 reports)

Gingival hyperplasia treatments and more:

Gingival hyperplasia (1,228 reports)

How severe was Gingival hyperplasia and when was it recovered:

Gingival hyperplasia in Amlodipine

Expand to all the drugs that have ingredients of amlodipine besylate:

Gingival hyperplasia and drugs with ingredients of amlodipine besylate (316 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival hyperplasia:

Gingival hyperplasia (154 drugs)

Browse all the conditions that are associated with Gingival hyperplasia:

Gingival hyperplasia (263 conditions)

Related publications that referenced our studies

Raheel SA, Kujan OB, Tarakji B, Umar D, Ibrahim S, "Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction", Journal of advanced pharmaceutical technology & research, 2016 Jan .
Raheel SA, Kujan OB, Tarakji B, Umar D, Ibrahim S, "Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction", Journal of advanced pharmaceutical technology & research, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.