Amlodipine and Pituitary-dependent cushing's syndrome - a phase IV clinical study of FDA data

Summary:

Pituitary-dependent cushing's syndrome is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, also take Lyrica, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Pituitary-dependent cushing's syndrome when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Pituitary-dependent cushing's syndrome?

Pituitary-dependent cushing's syndrome (pituitary dependent hypercortisolism) is found to be associated with 38 drugs and 243 conditions by eHealthMe. Check the latest studies of Pituitary-dependent cushing's syndrome.

On Jul, 15, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 13 people (0.0%) have Pituitary-dependent cushing's syndrome.

Could Amlodipine cause Pituitary-dependent cushing's syndrome?

Among these 13 people:

What is the gender of people who have Pituitary-dependent cushing's syndrome when taking Amlodipine? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Pituitary-dependent cushing's syndrome when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have besides Pituitary-dependent cushing's syndrome? *

Weakness: 4 people, 30.77%
Weight Loss: 2 people, 15.38%
Back Disorder: 2 people, 15.38%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 15.38%
Cushingoid (obesity and weakening of the muscles): 2 people, 15.38%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 15.38%
Cancer - Throat Or Larynx: 2 people, 15.38%
Groin Abscess (pus in groin): 2 people, 15.38%
Osgood-Schlatter Disease (an overuse injury that occurs in the knee area of growing adolescents. it is caused by inflammation of the tendon below the kneecap): 2 people, 15.38%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 15.38%

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 38.46%
Diabetes: 4 people, 30.77%
Weight Decreased: 2 people, 15.38%
Hypotension (abnormally low blood pressure): 2 people, 15.38%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 15.38%
Hiv Infection: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.69%
Cardiac Failure Congestive: 1 person, 7.69%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Pituitary-dependent cushing's syndrome?

- Check whether Pituitary-dependent cushing's syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,829 reports)

Pituitary-dependent cushing's syndrome treatments and more:

Pituitary-dependent cushing's syndrome (2,534 reports)

How severe was Pituitary-dependent cushing's syndrome and when was it recovered:

Pituitary-dependent cushing's syndrome in Amlodipine

Expand to all the drugs that have ingredients of amlodipine besylate:

Pituitary-dependent cushing's syndrome and drugs with ingredients of amlodipine besylate (17 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pituitary-dependent cushing's syndrome:

Pituitary-dependent cushing's syndrome (38 drugs)

Browse all the conditions that are associated with Pituitary-dependent cushing's syndrome:

Pituitary-dependent cushing's syndrome (243 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.