Amlodipine and Primary progressive multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Primary progressive multiple sclerosis is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Norvasc, and have Asthma.

The phase IV clinical study analyzes which people have Primary progressive multiple sclerosis when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,833 Amlodipine users. Check the latest studies of Amlodipine.

What is Primary progressive multiple sclerosis?

Primary progressive multiple sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged) is found to be associated with 37 drugs and 70 conditions by eHealthMe. Check the latest studies of Primary progressive multiple sclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 16 people (0.0%) have Primary progressive multiple sclerosis.

Could Amlodipine cause Primary progressive multiple sclerosis?

Among these 16 people:

How long have people been on Amlodipine when they have Primary progressive multiple sclerosis? *

What is the gender of people who have Primary progressive multiple sclerosis when taking Amlodipine? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Primary progressive multiple sclerosis when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have besides Primary progressive multiple sclerosis? *

Visual Impairment: 13 people, 81.25%
Weight Decreased: 12 people, 75.00%
Eye Pain: 12 people, 75.00%
Fatigue (feeling of tiredness): 10 people, 62.50%
Weakness: 10 people, 62.50%
Headache (pain in head): 10 people, 62.50%
Fall: 10 people, 62.50%
Wrist Fracture: 9 people, 56.25%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 56.25%
Back Pain: 9 people, 56.25%

What are the existing conditions these people have? *

Asthma: 9 people, 56.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 31.25%
Visual Impairment: 3 people, 18.75%
Pain: 3 people, 18.75%
Muscle Spasms (muscle contraction): 3 people, 18.75%
Menopause (end of monthly cycles in women): 3 people, 18.75%
Fatigue (feeling of tiredness): 3 people, 18.75%
Constipation: 3 people, 18.75%
Bladder Spasm: 3 people, 18.75%
Back Pain: 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Primary progressive multiple sclerosis?

- Check whether Primary progressive multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,833 reports)

Primary progressive multiple sclerosis treatments and more:

Primary progressive multiple sclerosis (10,011 reports)

How severe was Primary progressive multiple sclerosis and when was it recovered:

Primary progressive multiple sclerosis in Amlodipine

Expand to all the drugs that have ingredients of amlodipine besylate:

Primary progressive multiple sclerosis and drugs with ingredients of amlodipine besylate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Primary progressive multiple sclerosis:

Primary progressive multiple sclerosis (37 drugs)

Browse all the conditions that are associated with Primary progressive multiple sclerosis:

Primary progressive multiple sclerosis (70 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.