Amlodipine and Stroke in evolution - a phase IV clinical study of FDA data

Summary:

Stroke in evolution is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Xarelto, and have Stroke.

The phase IV clinical study analyzes which people have Stroke in evolution when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Stroke in evolution?

Stroke in evolution (unstable stage in stroke syndrome in which the blockage is present but the syndrome has not progressed to the stage of completed stroke) is found to be associated with 38 drugs and 78 conditions by eHealthMe. Check the latest studies of Stroke in evolution.



On Jul, 21, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 16 people (0.0%) have Stroke in evolution.

Could Amlodipine cause Stroke in evolution?

Among these 16 people:

How long have people been on Amlodipine when they have Stroke in evolution? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke in evolution when taking Amlodipine? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Stroke in evolution when taking Amlodipine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 90.91 %

What are other drugs people take besides Amlodipine? *

  1. Xarelto: 12 people, 75.00%
  2. Celexa: 7 people, 43.75%
  3. Femara: 6 people, 37.50%
  4. Metformin: 6 people, 37.50%
  5. Pepcid: 5 people, 31.25%
  6. Lexapro: 3 people, 18.75%
  7. Plavix: 2 people, 12.50%
  8. Novolog: 2 people, 12.50%
  9. Aricept: 2 people, 12.50%
  10. Lotensin: 2 people, 12.50%

What are other side effects people have besides Stroke in evolution? *

  1. Fall: 6 people, 37.50%
  2. Bipolar Disorder (mood disorder): 6 people, 37.50%
  3. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 6 people, 37.50%
  4. Cerebral Haemorrhage (bleeding within the brain): 6 people, 37.50%
  5. Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 6 people, 37.50%
  6. Encephalopathy (functioning of the brain is affected by some agent or condition): 6 people, 37.50%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 12.50%
  8. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 12.50%
  9. Retroperitoneal Haemorrhage (bleeding between the peritoneum and the posterior abdominal wall): 2 people, 12.50%
  10. Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 2 people, 12.50%

What are the existing conditions these people have? *

  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 13 people, 81.25%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 11 people, 68.75%
  3. Cerebral Haemorrhage (bleeding within the brain): 4 people, 25.00%
  4. Iron Deficiency Anaemia: 2 people, 12.50%
  5. Cardiac Disorder: 2 people, 12.50%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
  7. Urinary Tract Infection: 2 people, 12.50%
  8. High Blood Cholesterol: 2 people, 12.50%
  9. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 6.25%
  10. Insomnia (sleeplessness): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Stroke in evolution?

- Check whether Stroke in evolution is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Stroke in evolution treatments and more:

How severe was Stroke in evolution and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke in evolution:

Browse all the conditions that are associated with Stroke in evolution:


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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