Amlodipine and Subcutaneous emphysema - a phase IV clinical study of FDA data

Summary:

Subcutaneous emphysema is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Breast cancer recurrent.

The phase IV clinical study analyzes which people have Subcutaneous emphysema when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,833 Amlodipine users. Check the latest studies of Amlodipine.

What is Subcutaneous emphysema?

Subcutaneous emphysema (smooth bulging of the skin) is found to be associated with 169 drugs and 526 conditions by eHealthMe. Check the latest studies of Subcutaneous emphysema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 31 people (0.01%) have Subcutaneous emphysema.

Could Amlodipine cause Subcutaneous emphysema?

Among these 31 people:

How long have people been on Amlodipine when they have Subcutaneous emphysema? *

What is the gender of people who have Subcutaneous emphysema when taking Amlodipine? *

female: 63.33 %
male: 36.67 %

What is the age of people who have Subcutaneous emphysema when taking Amlodipine? *

What are other drugs people take besides Amlodipine? *

What are other side effects people have besides Subcutaneous emphysema? *

Dyspnea (difficult or laboured breathing): 10 people, 32.26%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 9 people, 29.03%
Interstitial Lung Disease: 8 people, 25.81%
Pneumomediastinum (air is present in the mediastinum): 7 people, 22.58%
Fall: 7 people, 22.58%
Diarrhea: 7 people, 22.58%
Pain: 7 people, 22.58%
Pain In Extremity: 6 people, 19.35%
Anaemia (lack of blood): 6 people, 19.35%
Femur Fracture: 5 people, 16.13%

What are the existing conditions these people have? *

Breast Cancer Recurrent: 6 people, 19.35%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.13%
Cardiac Failure Congestive: 4 people, 12.90%
High Blood Cholesterol: 4 people, 12.90%
Interstitial Lung Disease: 3 people, 9.68%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 9.68%
Insomnia (sleeplessness): 3 people, 9.68%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 6.45%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.45%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Subcutaneous emphysema?

- Check whether Subcutaneous emphysema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Amlodipine (354,833 reports)

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Subcutaneous emphysema:

Subcutaneous emphysema (169 drugs)

Browse all the conditions that are associated with Subcutaneous emphysema:

Subcutaneous emphysema (526 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.