Amnesteem and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Amnesteem (isotretinoin), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Accutane, and have Insomnia.

The phase IV clinical study analyzes which people have C. diff when taking Amnesteem. It is created by eHealthMe based on reports of 7,301 people who have side effects when taking Amnesteem from the FDA, and is updated regularly.

What is Amnesteem?

Amnesteem has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 7,344 Amnesteem users. Check the latest studies of Amnesteem.

What is C. diff?

C. diff is found to be associated with 1,578 drugs and 1,776 conditions by eHealthMe. Check the latest studies of C. diff.

On Apr, 22, 2026

7,301 people reported to have side effects when taking Amnesteem.
Among them, 21 people (0.29%) have C. diff.

Among these 21 people:

How long have people been on Amnesteem when they have C. diff? *

What is the gender of people who have C. diff when taking Amnesteem? *

female: 47.62 %
male: 52.38 %

What is the age of people who have C. diff when taking Amnesteem? *

What are other drugs people take besides Amnesteem? *

What are other side effects people have besides C. diff? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 21 people, 100.00%
Inflammatory Bowel Disease: 21 people, 100.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 66.67%
Stress And Anxiety: 14 people, 66.67%
High Blood Cholesterol: 12 people, 57.14%
Colitis (inflammation of colon): 10 people, 47.62%
Dehydration (dryness resulting from the removal of water): 10 people, 47.62%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 10 people, 47.62%
Gallstones (stone formation by bile component): 10 people, 47.62%
Gastritis (inflammation of stomach): 10 people, 47.62%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 9 people, 42.86%
Sinusitis (inflammation of sinus): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Amnesteem and have C. diff?

- Check whether C. diff is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amnesteem:

Amnesteem (7,344 reports)

C. diff treatments and more:

C. diff (13,845 reports)

Browse all side effects of Amnesteem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

C. diff (1,578 drugs)

Browse all the conditions that are associated with C. diff:

C. diff (1,776 conditions)

Related publications that referenced our studies

Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Amnesteem) and Amnesteem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.