Amnesteem and Syncope - a phase IV clinical study of FDA data

Summary:

Syncope is reported as a side effect among people who take Amnesteem (isotretinoin), especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months also take Accutane, and have Eczema.

The phase IV clinical study analyzes which people have Syncope when taking Amnesteem. It is created by eHealthMe based on reports of 7,301 people who have side effects when taking Amnesteem from the FDA, and is updated regularly.

What is Amnesteem?

Amnesteem has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 7,344 Amnesteem users. Check the latest studies of Amnesteem.

What is Syncope?

Syncope (loss of consciousness with an inability to maintain postural tone) is found to be associated with 3,442 drugs and 3,518 conditions by eHealthMe. Check the latest studies of Syncope.

On Apr, 10, 2026

7,301 people reported to have side effects when taking Amnesteem.
Among them, 28 people (0.38%) have Syncope.

Among these 28 people:

How long have people been on Amnesteem when they have Syncope? *

What is the gender of people who have Syncope when taking Amnesteem? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Syncope when taking Amnesteem? *

What are other drugs people take besides Amnesteem? *

What are other side effects people have besides Syncope? *

Dizziness: 8 people, 28.57%
Inflammatory Bowel Disease: 7 people, 25.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 21.43%
Depression: 6 people, 21.43%
Joint Pain: 5 people, 17.86%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 17.86%
Weakness: 4 people, 14.29%
Post Concussion Syndrome: 4 people, 14.29%
Chest Pain: 4 people, 14.29%
Mobility Decreased (ability to move is reduced): 4 people, 14.29%

What are the existing conditions these people have? *

Sinusitis (inflammation of sinus): 2 people, 7.14%
Premenstrual Syndrome: 2 people, 7.14%
Pain: 2 people, 7.14%
Laryngitis (inflammation of the larynx): 2 people, 7.14%
Irritable Bowel Syndrome: 2 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.14%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 7.14%
Sleep Disorder: 1 person, 3.57%
Quit Smoking: 1 person, 3.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Amnesteem and have Syncope?

- Check whether Syncope is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amnesteem:

Amnesteem (7,344 reports)

Syncope treatments and more:

Syncope (131,321 reports)

Browse all side effects of Amnesteem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Syncope:

Syncope (3,442 drugs)

Browse all the conditions that are associated with Syncope:

Syncope (3,518 conditions)

Related publications that referenced our studies

Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Amnesteem) and Amnesteem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.