Amoxicillin and Water intoxication - a phase IV clinical study of FDA data

Summary:

Water intoxication is reported as a side effect among people who take Amoxicillin (amoxicillin), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Dolutegravir, and have Cytomegalovirus infection.

The phase IV clinical study analyzes which people have Water intoxication when taking Amoxicillin. It is created by eHealthMe based on reports of 95,831 people who have side effects when taking Amoxicillin from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Water intoxication?

Water intoxication (water poisoning) is found to be associated with 79 drugs and 347 conditions by eHealthMe. Check the latest studies of Water intoxication.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

95,831 people reported to have side effects when taking Amoxicillin.
Among them, 12 people (0.01%) have Water intoxication.

Could Amoxicillin cause Water intoxication?

Among these 12 people:

How long have people been on Amoxicillin when they have Water intoxication? *

What is the gender of people who have Water intoxication when taking Amoxicillin? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Water intoxication when taking Amoxicillin? *

What are other drugs people take besides Amoxicillin? *

Albuterol: 7 people, 58.33%
Truvada: 7 people, 58.33%
Atovaquone: 7 people, 58.33%
Descovy: 7 people, 58.33%
Dolutegravir: 7 people, 58.33%
Famotidine: 6 people, 50.00%
Levofloxacin: 6 people, 50.00%
Acetaminophen: 5 people, 41.67%
Trazodone Hydrochloride: 4 people, 33.33%
Verapamil Hydrochloride: 4 people, 33.33%

What are other side effects people have besides Water intoxication? *

Itching: 7 people, 58.33%
Pneumonia: 7 people, 58.33%
Alcohol Poisoning: 7 people, 58.33%
Drug Eruption (adverse drug reaction of the skin): 7 people, 58.33%
Folliculitis (infection of hair root): 7 people, 58.33%
Gastroenteritis (inflammation of stomach and intestine): 7 people, 58.33%
Lip Erosion (peeling off of lip): 7 people, 58.33%
Oral Candidiasis (fungal infection of mouth): 7 people, 58.33%
Pericoronitis (inflammation of the gingiva surrounding the crown of a tooth): 7 people, 58.33%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 7 people, 58.33%

What are the existing conditions these people have? *

Pneumonia: 7 people, 58.33%
Pericoronitis (inflammation of the gingiva surrounding the crown of a tooth): 7 people, 58.33%
Hiv Infection: 7 people, 58.33%
Gastroenteritis (inflammation of stomach and intestine): 7 people, 58.33%
Cytomegalovirus Infection: 7 people, 58.33%
Itching: 5 people, 41.67%
Alcohol Poisoning: 5 people, 41.67%
High Blood Pressure: 4 people, 33.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 25.00%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and have Water intoxication?

- Check whether Water intoxication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amoxicillin:

Amoxicillin (99,235 reports)

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Water intoxication:

Water intoxication (79 drugs)

Browse all the conditions that are associated with Water intoxication:

Water intoxication (347 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin (the active ingredients of Amoxicillin) and Amoxicillin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.