Ampicillin and sulbactam and Febrile neutropenia - a phase IV clinical study of FDA data

Summary:

Febrile neutropenia is reported as a side effect among people who take Ampicillin and sulbactam (ampicillin sodium; sulbactam sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carboplatin, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Febrile neutropenia when taking Ampicillin and sulbactam. It is created by eHealthMe based on reports of 962 people who have side effects when taking Ampicillin and sulbactam from the FDA, and is updated regularly.

What is Ampicillin and sulbactam?

Ampicillin and sulbactam has active ingredients of ampicillin sodium; sulbactam sodium. eHealthMe is studying from 969 Ampicillin and sulbactam users. Check the latest studies of Ampicillin and sulbactam.

What is Febrile neutropenia?

Febrile neutropenia (fever with reduced white blood cells) is found to be associated with 1,586 drugs and 1,875 conditions by eHealthMe. Check the latest studies of Febrile neutropenia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

962 people reported to have side effects when taking Ampicillin and sulbactam.
Among them, 11 people (1.14%) have Febrile neutropenia.

Could Ampicillin and sulbactam cause Febrile neutropenia?

Among these 11 people:

How long have people been on Ampicillin and sulbactam when they have Febrile neutropenia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Febrile neutropenia when taking Ampicillin and sulbactam? *

  • female: 36.36 %
  • male: 63.64 %

What is the age of people who have Febrile neutropenia when taking Ampicillin and sulbactam? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 18.18 %
  • 40-49: 0.0 %
  • 50-59: 18.18 %
  • 60+: 54.55 %

What are other drugs people take besides Ampicillin and sulbactam? *

  1. Carboplatin: 3 people, 27.27%
  2. Xospata: 2 people, 18.18%
  3. Fentanyl: 2 people, 18.18%
  4. Lactulose: 2 people, 18.18%
  5. Imfinzi: 2 people, 18.18%
  6. Hydrocortisone Sodium Succinate: 2 people, 18.18%
  7. Hydrea: 2 people, 18.18%
  8. Vitamins: 2 people, 18.18%
  9. Furosemide: 2 people, 18.18%
  10. Fluorouracil: 2 people, 18.18%

What are other side effects people have besides Febrile neutropenia? *

  1. White Blood Cell Count Decreased: 2 people, 18.18%
  2. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 2 people, 18.18%
  3. Diarrhea: 2 people, 18.18%
  4. Haemoglobin Decreased: 2 people, 18.18%
  5. Hepatotoxicity (chemical-driven liver damage): 2 people, 18.18%
  6. Thrombocytopenia (decrease of platelets in blood): 2 people, 18.18%
  7. Nausea (feeling of having an urge to vomit): 2 people, 18.18%
  8. Neutropenic Colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition): 2 people, 18.18%
  9. Meningitis Pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 2 people, 18.18%
  10. Pneumococcal Bacteraemia (infection confirmed by the isolation of streptococcus pneumoniae): 2 people, 18.18%

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 27.27%
  2. Mycobacterium Avium Complex Infection: 2 people, 18.18%
  3. Fungal Infection: 2 people, 18.18%
  4. Herpes Simplex (herpes simplex is a common viral infection): 2 people, 18.18%
  5. Herpes Zoster: 2 people, 18.18%
  6. Hiv Infection: 2 people, 18.18%
  7. Pneumonia Pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs): 2 people, 18.18%
  8. Meningitis Pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 2 people, 18.18%
  9. Oral Bacterial Infection (bacterial infection of mouth): 2 people, 18.18%
  10. Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Ampicillin and sulbactam and have Febrile neutropenia?

- Check whether Febrile neutropenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ampicillin and sulbactam:

Febrile neutropenia treatments and more:

How severe was Febrile neutropenia and when was it recovered:

Expand to all the drugs that have ingredients of ampicillin sodium; sulbactam sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ampicillin and sulbactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Febrile neutropenia:

Browse all the conditions that are associated with Febrile neutropenia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ampicillin sodium; sulbactam sodium (the active ingredients of Ampicillin and sulbactam) and Ampicillin and sulbactam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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