Amrix and Arthritis - a phase IV clinical study of FDA data

Summary:

Arthritis is reported as a side effect among people who take Amrix (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Arthritis when taking Amrix. It is created by eHealthMe based on reports of 898 people who have side effects when taking Amrix from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Arthritis?

Arthritis (form of joint disorder that involves inflammation of one or more joints) is found to be associated with 1,961 drugs and 2,259 conditions by eHealthMe. Check the latest studies of Arthritis.

On Jul, 09, 2026

898 people reported to have side effects when taking Amrix.
Among them, 14 people (1.56%) have Arthritis.

Among these 14 people:

What is the gender of people who have Arthritis when taking Amrix? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Arthritis when taking Amrix? *

What are other drugs people take besides Amrix? *

What are other side effects people have besides Arthritis? *

Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 35.71%
Pain: 4 people, 28.57%
Chest Pain: 3 people, 21.43%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 21.43%
Gait Disturbance: 3 people, 21.43%
Weight Decreased: 3 people, 21.43%
Indigestion: 3 people, 21.43%
Cough: 2 people, 14.29%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 14.29%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 14.29%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 42.86%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 21.43%
Osteoporosis (bones weak and more likely to break): 2 people, 14.29%
Neck Pain: 2 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%
Vitamin B12 Deficiency: 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Muscle Disorder (muscle disease): 1 person, 7.14%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Amrix and have Arthritis?

- Check whether Arthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amrix:

Amrix (1,130 reports)

Arthritis treatments and more:

Arthritis (188,667 reports)

Browse all side effects of Amrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthritis:

Arthritis (1,961 drugs)

Browse all the conditions that are associated with Arthritis:

Arthritis (2,259 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Amrix) and Amrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.