Mycophenolate mofetil and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is reported as a side effect among people who take Mycophenolate mofetil (mycophenolate mofetil), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Tacrolimus, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Brain herniation when taking Mycophenolate mofetil. It is created by eHealthMe based on reports of 93,176 people who have side effects when taking Mycophenolate mofetil from the FDA, and is updated regularly.

What is Mycophenolate mofetil?

Mycophenolate mofetil has active ingredients of mycophenolate mofetil. It is often used in myasthenia gravis. eHealthMe is studying from 93,460 Mycophenolate mofetil users. Check the latest studies of Mycophenolate mofetil.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 337 drugs and 975 conditions by eHealthMe. Check the latest studies of Brain herniation.

On Jul, 09, 2026

93,176 people reported to have side effects when taking Mycophenolate mofetil.
Among them, 73 people (0.08%) have Brain herniation.

Could Mycophenolate mofetil cause Brain herniation?

Among these 73 people:

How long have people been on Mycophenolate mofetil when they have Brain herniation? *

What is the gender of people who have Brain herniation when taking Mycophenolate mofetil? *

female: 38.24 %
male: 61.76 %

What is the age of people who have Brain herniation when taking Mycophenolate mofetil? *

What are other drugs people take besides Mycophenolate mofetil? *

Tacrolimus: 36 people, 49.32%
Cefazolin: 23 people, 31.51%
Vancomycin: 18 people, 24.66%
Prednisone: 17 people, 23.29%
Methylprednisolone: 17 people, 23.29%
Meropenem: 16 people, 21.92%
Insulin: 10 people, 13.70%
Acetylsalicylic Acid: 8 people, 10.96%
Piperacillin And Tazobactam: 8 people, 10.96%
Sulfamethoxazole And Trimethoprim: 7 people, 9.59%

What are other side effects people have besides Brain herniation? *

Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 28 people, 38.36%
Subarachnoid Haemorrhage (blood leaks into the space between two membranes that surround the brain): 24 people, 32.88%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 20 people, 27.40%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 17 people, 23.29%
Haemorrhage Intracranial (bleeding within the skull): 16 people, 21.92%
Pneumonia Fungal: 15 people, 20.55%
Depressed Level Of Consciousness: 14 people, 19.18%
Septic Shock (shock due to blood infection): 13 people, 17.81%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 13 people, 17.81%
Subdural Haemorrhage (bleeding between the skull and the surface of the brain): 13 people, 17.81%

What are the existing conditions these people have? *

Pathogen Resistance: 12 people, 16.44%
Immunodeficiency Disorders: 12 people, 16.44%
Empyema (collection of pus in a cavity in the body): 10 people, 13.70%
Escherichia Bacteraemia (presence of bacteria escherichia coli in the blood): 9 people, 12.33%
Diabetes: 8 people, 10.96%
Pneumonia: 7 people, 9.59%
Acute Graft Versus Host Disease In Skin (acute complication on skin following an allogeneic tissue/blood transplant): 4 people, 5.48%
Bone Marrow Conditioning Regimen: 4 people, 5.48%
Multiple Myeloma (cancer of the plasma cells): 4 people, 5.48%
Graft Versus Host Disease In Liver (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the liver): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take Mycophenolate mofetil and have Brain herniation?

- Check whether Brain herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mycophenolate mofetil:

Mycophenolate mofetil (93,460 reports)

Browse all side effects of Mycophenolate mofetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain herniation:

Brain herniation (337 drugs)

Browse all the conditions that are associated with Brain herniation:

Brain herniation (975 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mycophenolate mofetil (the active ingredients of Mycophenolate mofetil) and Mycophenolate mofetil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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