Amrix and Multiple sclerosis relapse - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis relapse is reported as a side effect among people who take Amrix (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, also take Gilenya, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Multiple sclerosis relapse when taking Amrix. It is created by eHealthMe based on reports of 898 people who have side effects when taking Amrix from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Multiple sclerosis relapse?

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,030 drugs and 943 conditions by eHealthMe. Check the latest studies of Multiple sclerosis relapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

898 people reported to have side effects when taking Amrix.
Among them, 21 people (2.34%) have Multiple sclerosis relapse.

Could Amrix cause Multiple sclerosis relapse?

Among these 21 people:

What is the gender of people who have Multiple sclerosis relapse when taking Amrix? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Multiple sclerosis relapse when taking Amrix? *

What are other drugs people take besides Amrix? *

What are other side effects people have besides Multiple sclerosis relapse? *

Fatigue (feeling of tiredness): 4 people, 19.05%
Monocyte Count Increased: 3 people, 14.29%
Low Density Lipoprotein Increased (cholesterol increased in blood): 3 people, 14.29%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 3 people, 14.29%
Weakness: 3 people, 14.29%
Injection Site Haematoma (localized swelling filled with blood at injection site): 3 people, 14.29%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 3 people, 14.29%
High Blood Pressure: 3 people, 14.29%
High Blood Cholesterol: 3 people, 14.29%
Hair Loss: 3 people, 14.29%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 21 people, 100.00%
Pain: 5 people, 23.81%
Nausea (feeling of having an urge to vomit): 5 people, 23.81%
Vitamin D Decreased: 2 people, 9.52%
Multiple Allergies (allergy to multiple agents): 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%
Bipolar Disorder (mood disorder): 2 people, 9.52%
Vulvovaginal Dryness: 1 person, 4.76%
Sleep Disorder: 1 person, 4.76%
Indigestion: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Amrix and have Multiple sclerosis relapse?

- Check whether Multiple sclerosis relapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amrix:

Amrix (1,130 reports)

Browse all side effects of Amrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (1,030 drugs)

Browse all the conditions that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (943 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Amrix) and Amrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.