Amrix and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Amrix (cyclobenzaprine hydrochloride), especially for people who are female, 60+ old, also take Lisinopril, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Weakness when taking Amrix. It is created by eHealthMe based on reports of 898 people who have side effects when taking Amrix from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Weakness?

Weakness is found to be associated with 3,639 drugs and 6,578 conditions by eHealthMe. Check the latest studies of Weakness.



On Jan, 28, 2026

898 people reported to have side effects when taking Amrix.
Among them, 27 people (3.01%) have Weakness.

Could Amrix cause Weakness?

Among these 27 people:

What is the gender of people who have Weakness when taking Amrix? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Weakness when taking Amrix? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 27.27 %
  • 40-49: 13.64 %
  • 50-59: 13.64 %
  • 60+: 45.45 %

What are other drugs people take besides Amrix? *

  1. Lisinopril: 9 people, 33.33%
  2. Digoxin: 8 people, 29.63%
  3. Fish Oil: 5 people, 18.52%
  4. Warfarin Sodium: 5 people, 18.52%
  5. Nexium: 5 people, 18.52%
  6. Toprol-Xl: 5 people, 18.52%
  7. Veetids: 4 people, 14.81%
  8. Gilenya: 4 people, 14.81%
  9. Carvedilol: 4 people, 14.81%
  10. Synthroid: 4 people, 14.81%

What are other side effects people have besides Weakness? *

  1. Pain: 7 people, 25.93%
  2. Fatigue (feeling of tiredness): 6 people, 22.22%
  3. Dyspnea (difficult or laboured breathing): 6 people, 22.22%
  4. Injury: 5 people, 18.52%
  5. Fall: 5 people, 18.52%
  6. Dizziness: 5 people, 18.52%
  7. Stress And Anxiety: 5 people, 18.52%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 18.52%
  9. Balance Disorder: 5 people, 18.52%
  10. Depression: 5 people, 18.52%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 18.52%
  2. Pain: 4 people, 14.81%
  3. Muscle Spasms (muscle contraction): 3 people, 11.11%
  4. Heart Rate Increased: 3 people, 11.11%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.41%
  6. Headache (pain in head): 2 people, 7.41%
  7. Stress And Anxiety: 2 people, 7.41%
  8. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 7.41%
  9. Cardiac Disorder: 2 people, 7.41%
  10. Neuralgia (pain in one or more nerves): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Amrix and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amrix:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of cyclobenzaprine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Amrix) and Amrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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