Androgel and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is reported as a side effect among people who take Androgel (testosterone), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Synthroid, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Knee joint replacement when taking Androgel. It is created by eHealthMe based on reports of 25,097 people who have side effects when taking Androgel from the FDA, and is updated regularly.

What is Androgel?

Androgel has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 25,763 Androgel users. Check the latest studies of Androgel.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 953 drugs and 1,228 conditions by eHealthMe. Check the latest studies of Knee joint replacement.

On Jul, 07, 2026

25,097 people reported to have side effects when taking Androgel.
Among them, 20 people (0.08%) have Knee joint replacement.

Could Androgel cause Knee joint replacement?

Among these 20 people:

How long have people been on Androgel when they have Knee joint replacement? *

What is the gender of people who have Knee joint replacement when taking Androgel? *

female: 5 %
male: 95 %

What is the age of people who have Knee joint replacement when taking Androgel? *

What are other drugs people take besides Androgel? *

What are other side effects people have besides Knee joint replacement? *

Depression: 3 people, 15.00%
Gait Disturbance: 3 people, 15.00%
Weakness: 3 people, 15.00%
Chest Pain: 3 people, 15.00%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 15.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 10.00%
Fatigue (feeling of tiredness): 2 people, 10.00%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 10.00%
Sleep Apnea Syndrome: 2 people, 10.00%
Drug Ineffective: 2 people, 10.00%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 35.00%
High Blood Pressure: 6 people, 30.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 25.00%
Asthma: 5 people, 25.00%
Blood Testosterone Decreased: 5 people, 25.00%
Diabetes: 3 people, 15.00%
Hypersensitivity: 3 people, 15.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 10.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 10.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Androgel and have Knee joint replacement?

- Check whether Knee joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Androgel:

Androgel (25,763 reports)

Browse all side effects of Androgel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee joint replacement:

Knee joint replacement (953 drugs)

Browse all the conditions that are associated with Knee joint replacement:

Knee joint replacement (1,228 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on testosterone (the active ingredients of Androgel) and Androgel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.