Androgel and Personality change - a phase IV clinical study of FDA data

Summary:

Personality change is reported as a side effect among people who take Androgel (testosterone), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Cymbalta, and have Blood testosterone decreased.

The phase IV clinical study analyzes which people have Personality change when taking Androgel. It is created by eHealthMe based on reports of 25,097 people who have side effects when taking Androgel from the FDA, and is updated regularly.

What is Androgel?

Androgel has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 25,763 Androgel users. Check the latest studies of Androgel.

What is Personality change?

Personality change is found to be associated with 725 drugs and 947 conditions by eHealthMe. Check the latest studies of Personality change.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

25,097 people reported to have side effects when taking Androgel.
Among them, 24 people (0.1%) have Personality change.

Could Androgel cause Personality change?

Among these 24 people:

How long have people been on Androgel when they have Personality change? *

What is the gender of people who have Personality change when taking Androgel? *

female: 0.0 %
male: 100 %

What is the age of people who have Personality change when taking Androgel? *

What are other drugs people take besides Androgel? *

What are other side effects people have besides Personality change? *

Anger: 8 people, 33.33%
Mood Swings (an extreme or rapid change in mood): 6 people, 25.00%
Feeling Abnormal: 5 people, 20.83%
Memory Loss: 5 people, 20.83%
Abnormal Behavior: 4 people, 16.67%
Depression: 4 people, 16.67%
Therapeutic Response Unexpected: 4 people, 16.67%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 12.50%
Aggression: 3 people, 12.50%
Drug Ineffective: 3 people, 12.50%

What are the existing conditions these people have? *

Blood Testosterone Decreased: 13 people, 54.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
High Blood Pressure: 2 people, 8.33%
Stress And Anxiety: 2 people, 8.33%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 4.17%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.17%
Depression: 1 person, 4.17%
Erection Problems: 1 person, 4.17%
High Blood Cholesterol: 1 person, 4.17%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Androgel and have Personality change?

- Check whether Personality change is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Androgel:

Androgel (25,763 reports)

Browse all side effects of Androgel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Personality change:

Personality change (725 drugs)

Browse all the conditions that are associated with Personality change:

Personality change (947 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on testosterone (the active ingredients of Androgel) and Androgel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.