Antabuse and Aggression - a phase IV clinical study of FDA data

Summary:

Aggression is reported as a side effect among people who take Antabuse (disulfiram), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Olanzapine, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Aggression when taking Antabuse. It is created by eHealthMe based on reports of 933 people who have side effects when taking Antabuse from the FDA, and is updated regularly.

What is Antabuse?

Antabuse has active ingredients of disulfiram. It is often used in alcoholism. eHealthMe is studying from 1,182 Antabuse users. Check the latest studies of Antabuse.

What is Aggression?

Aggression is found to be associated with 1,529 drugs and 1,965 conditions by eHealthMe. Check the latest studies of Aggression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

933 people reported to have side effects when taking Antabuse.
Among them, 28 people (3.0%) have Aggression.

Among these 28 people:

How long have people been on Antabuse when they have Aggression? *

What is the gender of people who have Aggression when taking Antabuse? *

female: 52 %
male: 48 %

What is the age of people who have Aggression when taking Antabuse? *

What are other drugs people take besides Antabuse? *

What are other side effects people have besides Aggression? *

Stress And Anxiety: 9 people, 32.14%
Agitation (state of anxiety or nervous excitement): 8 people, 28.57%
Psychomotor Hyperactivity (feelings of extreme restlessness): 8 people, 28.57%
Alcohol Poisoning: 8 people, 28.57%
Disturbance In Attention: 7 people, 25.00%
Nightmares (unpleasant dreams): 6 people, 21.43%
Irritability: 6 people, 21.43%
Suicidal Ideation: 5 people, 17.86%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 5 people, 17.86%
Confusional State: 5 people, 17.86%

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 21.43%
Insomnia (sleeplessness): 3 people, 10.71%
Colitis (inflammation of colon): 3 people, 10.71%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 10.71%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.57%
Quit Smoking: 1 person, 3.57%
Psychomotor Hyperactivity (feelings of extreme restlessness): 1 person, 3.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.57%
Dyspnea (difficult or laboured breathing): 1 person, 3.57%
Depression: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Antabuse and have Aggression?

- Check whether Aggression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Antabuse:

Antabuse (1,182 reports)

Aggression treatments and more:

Aggression (65,312 reports)

Browse all side effects of Antabuse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aggression:

Aggression (1,529 drugs)

Browse all the conditions that are associated with Aggression:

Aggression (1,965 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on disulfiram (the active ingredients of Antabuse) and Antabuse (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.