Apixaban and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is reported as a side effect among people who take Apixaban (apixaban), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Movicol, and have Stroke.

The phase IV clinical study analyzes which people have Hypertensive crisis when taking Apixaban. It is created by eHealthMe based on reports of 60,044 people who have side effects when taking Apixaban from the FDA, and is updated regularly.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 786 drugs and 932 conditions by eHealthMe. Check the latest studies of Hypertensive crisis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

60,044 people reported to have side effects when taking Apixaban.
Among them, 64 people (0.11%) have Hypertensive crisis.

Could Apixaban cause Hypertensive crisis?

Among these 64 people:

How long have people been on Apixaban when they have Hypertensive crisis? *

What is the gender of people who have Hypertensive crisis when taking Apixaban? *

female: 59.32 %
male: 40.68 %

What is the age of people who have Hypertensive crisis when taking Apixaban? *

What are other drugs people take besides Apixaban? *

What are other side effects people have besides Hypertensive crisis? *

Nausea (feeling of having an urge to vomit): 10 people, 15.62%
Disturbance In Attention: 9 people, 14.06%
Decreased Interest: 8 people, 12.50%
Confusion: 8 people, 12.50%
Balance Disorder: 8 people, 12.50%
Visual Impairment: 8 people, 12.50%
Cerebral Haemorrhage (bleeding within the brain): 6 people, 9.38%
Dyspnea (difficult or laboured breathing): 6 people, 9.38%
C-Reactive Protein Abnormal: 5 people, 7.81%
Dizziness: 5 people, 7.81%

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 24 people, 37.50%
High Blood Pressure: 23 people, 35.94%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 20.31%
Pain: 9 people, 14.06%
Prostate Cancer: 6 people, 9.38%
Mitral Valve Incompetence (inefficient heart valve): 5 people, 7.81%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 7.81%
Post Procedural Hypothyroidism: 5 people, 7.81%
Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 5 people, 7.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 7.81%

* Approximation only. Some reports may have incomplete information.

Do you take Apixaban and have Hypertensive crisis?

- Check whether Hypertensive crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apixaban:

Apixaban (60,351 reports)

Browse all side effects of Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive crisis:

Hypertensive crisis (786 drugs)

Browse all the conditions that are associated with Hypertensive crisis:

Hypertensive crisis (932 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Apixaban) and Apixaban (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.