Aprepitant and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Aprepitant (aprepitant), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Nausea.

The phase IV clinical study analyzes which people have Stroke when taking Aprepitant. It is created by eHealthMe based on reports of 6,989 people who have side effects when taking Aprepitant from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,345 drugs and 3,024 conditions by eHealthMe. Check the latest studies of Stroke.

On Feb, 22, 2026

6,989 people reported to have side effects when taking Aprepitant.
Among them, 26 people (0.37%) have Stroke.

Among these 26 people:

How long have people been on Aprepitant when they have Stroke? *

What is the gender of people who have Stroke when taking Aprepitant? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Stroke when taking Aprepitant? *

What are other drugs people take besides Aprepitant? *

What are other side effects people have besides Stroke? *

Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 10 people, 38.46%
Thrombocytopenia (decrease of platelets in blood): 9 people, 34.62%
Febrile Neutropenia (fever with reduced white blood cells): 8 people, 30.77%
White Blood Cell Count Decreased: 7 people, 26.92%
Lactic Acidosis (low ph in body tissues): 7 people, 26.92%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 7 people, 26.92%
Pulmonary Embolism (blockage of the main artery of the lung): 7 people, 26.92%
Atrial Thrombosis (blood clot that develops in an artery): 7 people, 26.92%
Encephalopathy (functioning of the brain is affected by some agent or condition): 7 people, 26.92%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 7 people, 26.92%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 30.77%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 7 people, 26.92%
Pain: 6 people, 23.08%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 4 people, 15.38%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 15.38%
Cough: 4 people, 15.38%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 15.38%
Dyspnea (difficult or laboured breathing): 4 people, 15.38%
Bladder Spasm: 4 people, 15.38%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Aprepitant and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aprepitant:

Aprepitant (6,992 reports)

Stroke treatments and more:

Stroke (334,634 reports)

Browse all side effects of Aprepitant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,345 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,024 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aprepitant (the active ingredients of Aprepitant) and Aprepitant (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.