Apresoline and Diplopia - a phase IV clinical study of FDA data
Summary:
Diplopia is reported as a side effect among people who take Apresoline (hydralazine hydrochloride), especially for people who are male, 60+ old, also take Aredia, and have Multiple myeloma.
The phase IV clinical study analyzes which people have Diplopia when taking Apresoline. It is created by eHealthMe based on reports of 2,441 people who have side effects when taking Apresoline from the FDA, and is updated regularly.
What is Apresoline?
Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.
What is Diplopia?
Diplopia (double vision) is found to be associated with 1,427 drugs and 1,895 conditions by eHealthMe. Check the latest studies of Diplopia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
2,441 people reported to have side effects when taking Apresoline.
Among them, 34 people (1.39%) have Diplopia.

Among these 34 people:
What is the gender of people who have Diplopia when taking Apresoline? *
- female: 39.39 %
- male: 60.61 %
What is the age of people who have Diplopia when taking Apresoline? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 3.12 %
- 60+: 96.88 %
What are other drugs people take besides Apresoline? *
- Aredia: 30 people, 88.24%
- Protonix: 29 people, 85.29%
- Prednisone: 24 people, 70.59%
- Centrum: 18 people, 52.94%
- Levaquin: 18 people, 52.94%
- Zometa: 18 people, 52.94%
- Celexa: 17 people, 50.00%
- Augmentin '125': 17 people, 50.00%
- Prednisolone: 17 people, 50.00%
- Oxycontin: 17 people, 50.00%
What are other side effects people have besides Diplopia? *
- Osteomyelitis (infection of bone): 32 people, 94.12%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 30 people, 88.24%
- Spinal Compression Fracture (fracture due to spinal compression on bone): 30 people, 88.24%
- Vision Blurred: 30 people, 88.24%
- Bone Disorder: 30 people, 88.24%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 30 people, 88.24%
- Enlarged Heart: 30 people, 88.24%
- Gallstones (stone formation by bile component): 30 people, 88.24%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 30 people, 88.24%
- Osteonecrosis Of Jaw (death of bone of jaw): 30 people, 88.24%
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 18 people, 52.94%
- Pain: 12 people, 35.29%
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 12 people, 35.29%
- Depression: 12 people, 35.29%
- Swelling: 1 person, 2.94%
- Procedural Pain: 1 person, 2.94%
- High Blood Cholesterol: 1 person, 2.94%
- Diabetes: 1 person, 2.94%
- Blood Pressure Abnormal: 1 person, 2.94%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 2.94%
* Approximation only. Some reports may have incomplete information.
Do you take Apresoline and have Diplopia?
- Check whether Diplopia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Apresoline:
- Apresoline (2,475 reports)
Diplopia treatments and more:
- Diplopia (32,466 reports)
How severe was Diplopia and when was it recovered:
Expand to all the drugs that have ingredients of hydralazine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Apresoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Diplopia:
- Diplopia (1,427 drugs)
Browse all the conditions that are associated with Diplopia:
- Diplopia (1,895 conditions)
Related publications that referenced our studies
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydralazine hydrochloride (the active ingredients of Apresoline) and Apresoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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