Oxycodone and Cardiac output decreased - a phase IV clinical study of FDA data

Summary:

Cardiac output decreased is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 40-49 old, also take Digoxin, and have Inflammation.

The phase IV clinical study analyzes which people have Cardiac output decreased when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Cardiac output decreased?

Cardiac output decreased is found to be associated with 236 drugs and 323 conditions by eHealthMe. Check the latest studies of Cardiac output decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 12 people (0.01%) have Cardiac output decreased.

Could Oxycodone cause Cardiac output decreased?

Among these 12 people:

What is the gender of people who have Cardiac output decreased when taking Oxycodone? *

female: 20 %
male: 80 %

What is the age of people who have Cardiac output decreased when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Cardiac output decreased? *

High Blood Pressure: 7 people, 58.33%
Fever: 7 people, 58.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 58.33%
Chest Pain: 7 people, 58.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 50.00%
Weakness: 6 people, 50.00%
Fall: 6 people, 50.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 50.00%
Confusional State: 6 people, 50.00%
Cardiac Disorder: 6 people, 50.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 5 people, 41.67%
Inflammation: 5 people, 41.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Rectal Cancer (cancer of rectum): 1 person, 8.33%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
Polymyalgia Rheumatica (pain in many muscles): 1 person, 8.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Iron Deficiency Anaemia: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Cardiac output decreased?

- Check whether Cardiac output decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac output decreased:

Cardiac output decreased (236 drugs)

Browse all the conditions that are associated with Cardiac output decreased:

Cardiac output decreased (323 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.