Apresoline and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Apresoline (hydralazine hydrochloride), especially for people who are male, 60+ old, also take Zofran, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Apresoline. It is created by eHealthMe based on reports of 2,441 people who have side effects when taking Apresoline from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,886 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

On Jul, 13, 2026

2,441 people reported to have side effects when taking Apresoline.
Among them, 35 people (1.43%) have Intestinal obstruction.

Could Apresoline cause Intestinal obstruction?

Among these 35 people:

What is the gender of people who have Intestinal obstruction when taking Apresoline? *

female: 22.86 %
male: 77.14 %

What is the age of people who have Intestinal obstruction when taking Apresoline? *

What are other drugs people take besides Apresoline? *

What are other side effects people have besides Intestinal obstruction? *

Sepsis (a severe blood infection that can lead to organ failure and death): 25 people, 71.43%
Anaemia (lack of blood): 23 people, 65.71%
Enlarged Heart: 23 people, 65.71%
Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 22 people, 62.86%
Dyspnea (difficult or laboured breathing): 21 people, 60.00%
Pain: 21 people, 60.00%
Pneumonia: 21 people, 60.00%
Bone Disorder: 19 people, 54.29%
Headache (pain in head): 19 people, 54.29%
Urinary Tract Infection: 19 people, 54.29%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 19 people, 54.29%
Pain: 4 people, 11.43%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 8.57%
Vomiting In Pregnancy: 2 people, 5.71%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 5.71%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 5.71%
Abdominal Pain: 2 people, 5.71%
Nausea (feeling of having an urge to vomit): 2 people, 5.71%
Immunodeficiency Disorders: 1 person, 2.86%
Hypotension (abnormally low blood pressure): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Apresoline and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apresoline:

Apresoline (2,475 reports)

Browse all side effects of Apresoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,886 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,613 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride (the active ingredients of Apresoline) and Apresoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.