Aptivus and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Aptivus (tipranavir), especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years also take Tenofovir Disoproxil Fumarate, and have Hiv infection.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Aptivus. It is created by eHealthMe based on reports of 1,057 people who have side effects when taking Aptivus from the FDA, and is updated regularly.

What is Aptivus?

Aptivus has active ingredients of tipranavir. eHealthMe is studying from 1,060 Aptivus users. Check the latest studies of Aptivus.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,496 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

1,057 people reported to have side effects when taking Aptivus.
Among them, 29 people (2.74%) have Liver function test abnormal.

Could Aptivus cause Liver function test abnormal?

Among these 29 people:

How long have people been on Aptivus when they have Liver function test abnormal? *

  • < 1 month: 6.67 %
  • 1 - 6 months: 20.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Liver function test abnormal when taking Aptivus? *

  • female: 29.17 %
  • male: 70.83 %

What is the age of people who have Liver function test abnormal when taking Aptivus? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.67 %
  • 20-29: 0.0 %
  • 30-39: 33.33 %
  • 40-49: 40.0 %
  • 50-59: 6.67 %
  • 60+: 13.33 %

What are other drugs people take besides Aptivus? *

  1. Raltegravir: 9 people, 31.03%
  2. Tenofovir Disoproxil Fumarate: 9 people, 31.03%
  3. Isentress: 8 people, 27.59%
  4. Prezista: 5 people, 17.24%
  5. Acyclovir: 5 people, 17.24%
  6. Clonazepam: 4 people, 13.79%
  7. Bactrim: 4 people, 13.79%
  8. Zolpidem Tartrate: 4 people, 13.79%
  9. Trizivir: 4 people, 13.79%
  10. Truvada: 4 people, 13.79%

What are other side effects people have besides Liver function test abnormal? *

  1. Hepatomegaly (abnormal enlargement of the liver): 6 people, 20.69%
  2. Alanine Aminotransferase Increased: 5 people, 17.24%
  3. Aspartate Aminotransferase Increased: 5 people, 17.24%
  4. Urine Amphetamine Positive: 4 people, 13.79%
  5. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 4 people, 13.79%
  6. Diarrhea: 4 people, 13.79%
  7. Transaminases Increased: 4 people, 13.79%
  8. Pancreatitis (inflammation of pancreas): 3 people, 10.34%
  9. Thrombocytopenia (decrease of platelets in blood): 2 people, 6.90%
  10. Ejection Fraction Abnormal (abnormality in percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 1 person, 3.45%

What are the existing conditions these people have? *

  1. Hiv Infection: 25 people, 86.21%

* Approximation only. Some reports may have incomplete information.

Do you take Aptivus and have Liver function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aptivus:

Liver function test abnormal treatments and more:

How severe was Liver function test abnormal and when was it recovered:

Expand to all the drugs that have ingredients of tipranavir:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aptivus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Browse all the conditions that are associated with Liver function test abnormal:


How the study uses the data?

The study uses data from the FDA. It is based on tipranavir (the active ingredients of Aptivus) and Aptivus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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