Aredia and Cervical spine flattening - a phase IV clinical study of FDA data

Summary:

Cervical spine flattening is reported as a side effect among people who take Aredia (pamidronate disodium), especially for people who are 50-59 old, have been taking the drug for 1 - 2 years also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Cervical spine flattening when taking Aredia. It is created by eHealthMe based on reports of 15,280 people who have side effects when taking Aredia from the FDA, and is updated regularly.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.

What is Cervical spine flattening?

Cervical spine flattening is found to be associated with 61 drugs and 69 conditions by eHealthMe. Check the latest studies of Cervical spine flattening.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

15,280 people reported to have side effects when taking Aredia.
Among them, 19 people (0.12%) have Cervical spine flattening.

Could Aredia cause Cervical spine flattening?

Among these 19 people:

How long have people been on Aredia when they have Cervical spine flattening? *

What is the age of people who have Cervical spine flattening when taking Aredia? *

What are other drugs people take besides Aredia? *

What are other side effects people have besides Cervical spine flattening? *

Pain: 18 people, 94.74%
Spinal Osteoarthritis (joint cartilage loss in spine): 18 people, 94.74%
Neck Pain: 16 people, 84.21%
Injury: 16 people, 84.21%
Emotional Distress: 16 people, 84.21%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 15 people, 78.95%
Bone Disorder: 15 people, 78.95%
Hypoaesthesia (reduced sense of touch or sensation): 15 people, 78.95%
Tooth Loss: 14 people, 73.68%
Intervertebral Disc Operation: 13 people, 68.42%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 15 people, 78.95%
Bone Cancer Metastatic: 14 people, 73.68%
Osteomyelitis (infection of bone): 4 people, 21.05%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Aredia and have Cervical spine flattening?

- Check whether Cervical spine flattening is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aredia:

Aredia (15,365 reports)

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cervical spine flattening:

Cervical spine flattening (61 drugs)

Browse all the conditions that are associated with Cervical spine flattening:

Cervical spine flattening (69 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pamidronate disodium (the active ingredients of Aredia) and Aredia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.