Arimidex and Systemic sclerosis - a phase IV clinical study of FDA data

Summary:

Systemic sclerosis is reported as a side effect among people who take Arimidex (anastrozole), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Systemic sclerosis when taking Arimidex. It is created by eHealthMe based on reports of 21,680 people who have side effects when taking Arimidex from the FDA, and is updated regularly.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

What is Systemic sclerosis?

Systemic sclerosis (an autoimmune or connective tissue disease. it is characterized by thickening of the skin) is found to be associated with 67 drugs and 161 conditions by eHealthMe. Check the latest studies of Systemic sclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

21,680 people reported to have side effects when taking Arimidex.
Among them, 12 people (0.06%) have Systemic sclerosis.

Could Arimidex cause Systemic sclerosis?

Among these 12 people:

How long have people been on Arimidex when they have Systemic sclerosis? *

What is the gender of people who have Systemic sclerosis when taking Arimidex? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Systemic sclerosis when taking Arimidex? *

What are other drugs people take besides Arimidex? *

What are other side effects people have besides Systemic sclerosis? *

Injury: 11 people, 91.67%
Spinal Osteoarthritis (joint cartilage loss in spine): 11 people, 91.67%
Skin Atrophy (wasting of skin): 11 people, 91.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 91.67%
Pruritus Genital (uneasy irritation of the skin of the vagina and the surrounding area): 11 people, 91.67%
Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 91.67%
General Physical Health Deterioration (weak health status): 11 people, 91.67%
Breast Cyst: 11 people, 91.67%
Metastases To Spine (cancer spreads to spine): 11 people, 91.67%
Metastases To Bone (cancer spreads to bone): 11 people, 91.67%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Arimidex and have Systemic sclerosis?

- Check whether Systemic sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arimidex:

Arimidex (22,642 reports)

Browse all side effects of Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic sclerosis:

Systemic sclerosis (67 drugs)

Browse all the conditions that are associated with Systemic sclerosis:

Systemic sclerosis (161 conditions)

Related publications that referenced our studies

Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on anastrozole (the active ingredients of Arimidex) and Arimidex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.