1. Home
  2. Analysis
  3. Arsenic-trioxide
  4. Pleural-effusion

Arsenic trioxide and Pleural effusion - a phase IV clinical study of FDA data

Summary:

Pleural effusion is reported as a side effect among people who take Arsenic trioxide (arsenic trioxide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tretinoin, and have Acute promyelocytic leukaemia.

The phase IV clinical study analyzes which people have Pleural effusion when taking Arsenic trioxide. It is created by eHealthMe based on reports of 984 people who have side effects when taking Arsenic trioxide from the FDA, and is updated regularly.

What is Arsenic trioxide?

Arsenic trioxide has active ingredients of arsenic trioxide. eHealthMe is studying from 990 Arsenic trioxide users. Check the latest studies of Arsenic trioxide.

What is Pleural effusion?

Pleural effusion (water on the lungs) is found to be associated with 2,221 drugs and 3,149 conditions by eHealthMe. Check the latest studies of Pleural effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

984 people reported to have side effects when taking Arsenic trioxide.
Among them, 29 people (2.95%) have Pleural effusion.

Could Arsenic trioxide cause Pleural effusion?

Among these 29 people:

How long have people been on Arsenic trioxide when they have Pleural effusion? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pleural effusion when taking Arsenic trioxide? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Pleural effusion when taking Arsenic trioxide? *

  • 0-1: 0.0 %
  • 2-9: 8.7 %
  • 10-19: 4.35 %
  • 20-29: 0.0 %
  • 30-39: 8.7 %
  • 40-49: 17.39 %
  • 50-59: 4.35 %
  • 60+: 56.52 %

What are other drugs people take besides Arsenic trioxide? *

  1. Tretinoin: 5 people, 17.24%
  2. Aspirin: 4 people, 13.79%
  3. Prednisone: 4 people, 13.79%
  4. Colchicine: 4 people, 13.79%
  5. Dexamethasone: 3 people, 10.34%
  6. Atra: 2 people, 6.90%
  7. Rabeprazole Sodium: 2 people, 6.90%
  8. Atenolol: 2 people, 6.90%
  9. Fluconazole: 2 people, 6.90%
  10. Neulasta: 2 people, 6.90%

What are other side effects people have besides Pleural effusion? *

  1. Pericardial Effusion (fluid around the heart): 13 people, 44.83%
  2. Fever: 10 people, 34.48%
  3. Hypotension (abnormally low blood pressure): 7 people, 24.14%
  4. Pneumonia: 7 people, 24.14%
  5. Pulmonary Oedema (fluid accumulation in the lungs): 7 people, 24.14%
  6. Dyspnea (difficult or laboured breathing): 6 people, 20.69%
  7. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 20.69%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 17.24%
  9. Leukocytosis (increased white blood cells): 4 people, 13.79%
  10. Electrocardiogram Qt Prolonged: 4 people, 13.79%

What are the existing conditions these people have? *

  1. Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 13 people, 44.83%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 20.69%
  3. Pericarditis (inflammation of the pericardium): 4 people, 13.79%
  4. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 3.45%
  5. Pre-Existing Disease: 1 person, 3.45%
  6. Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 3.45%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 3.45%
  8. Multiple Myeloma (cancer of the plasma cells): 1 person, 3.45%
  9. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 3.45%
  10. Joint Pain: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Arsenic trioxide and have Pleural effusion?

- Check whether Pleural effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arsenic trioxide:

Pleural effusion treatments and more:

How severe was Pleural effusion and when was it recovered:

Expand to all the drugs that have ingredients of arsenic trioxide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arsenic trioxide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pleural effusion:

Browse all the conditions that are associated with Pleural effusion:

How the study uses the data?

The study uses data from the FDA. It is based on arsenic trioxide (the active ingredients of Arsenic trioxide) and Arsenic trioxide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.