Artane and Anger - a phase IV clinical study of FDA data

Summary:

Anger is reported as a side effect among people who take Artane (trihexyphenidyl hydrochloride), especially for people who are male, 30-39 old, also take Risperdal, and have Pain.

The phase IV clinical study analyzes which people have Anger when taking Artane. It is created by eHealthMe based on reports of 3,524 people who have side effects when taking Artane from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Anger?

Anger is found to be associated with 1,243 drugs and 1,628 conditions by eHealthMe. Check the latest studies of Anger.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

3,524 people reported to have side effects when taking Artane.
Among them, 33 people (0.94%) have Anger.

Among these 33 people:

What is the gender of people who have Anger when taking Artane? *

female: 39.39 %
male: 60.61 %

What is the age of people who have Anger when taking Artane? *

What are other drugs people take besides Artane? *

What are other side effects people have besides Anger? *

Irritability: 14 people, 42.42%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 13 people, 39.39%
Depression: 13 people, 39.39%
Insomnia (sleeplessness): 13 people, 39.39%
Loss Of Consciousness: 10 people, 30.30%
Suicidal Ideation: 10 people, 30.30%
Stress And Anxiety: 10 people, 30.30%
Alanine Aminotransferase Increased: 10 people, 30.30%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 27.27%
Delusion (a false belief or opinion): 9 people, 27.27%

What are the existing conditions these people have? *

Pain: 8 people, 24.24%
Stress And Anxiety: 5 people, 15.15%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 15.15%
Bipolar Disorder (mood disorder): 4 people, 12.12%
High Blood Cholesterol: 2 people, 6.06%
Quit Smoking: 2 people, 6.06%
Depression: 2 people, 6.06%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 3.03%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 3.03%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Artane and have Anger?

- Check whether Anger is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Artane:

Artane (3,619 reports)

Anger treatments and more:

Anger (41,215 reports)

Browse all side effects of Artane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anger:

Anger (1,243 drugs)

Browse all the conditions that are associated with Anger:

Anger (1,628 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trihexyphenidyl hydrochloride (the active ingredients of Artane) and Artane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.