Artane and Cardiac disorder - a phase IV clinical study of FDA data

Summary:

Cardiac disorder is reported as a side effect among people who take Artane (trihexyphenidyl hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Clozaril, and have Cataplexy.

The phase IV clinical study analyzes which people have Cardiac disorder when taking Artane. It is created by eHealthMe based on reports of 3,524 people who have side effects when taking Artane from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Cardiac disorder?

Cardiac disorder is found to be associated with 2,041 drugs and 1,964 conditions by eHealthMe. Check the latest studies of Cardiac disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

3,524 people reported to have side effects when taking Artane.
Among them, 13 people (0.37%) have Cardiac disorder.

Among these 13 people:

How long have people been on Artane when they have Cardiac disorder? *

What is the gender of people who have Cardiac disorder when taking Artane? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Cardiac disorder when taking Artane? *

What are other drugs people take besides Artane? *

What are other side effects people have besides Cardiac disorder? *

Sleep Apnea Syndrome: 6 people, 46.15%
Cardiac Failure Congestive: 4 people, 30.77%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 23.08%
Eyelid Twitch (spontaneous and uncontrolled spasms of the muscles): 3 people, 23.08%
Aortic Thrombosis (formation of a blood clot inside aorta): 3 people, 23.08%
Drooling (drop saliva uncontrollably from the mouth): 3 people, 23.08%
Night Sweats (sweating in night): 3 people, 23.08%
Ascites (accumulation of fluid in the abdominal cavity): 3 people, 23.08%
Scar: 3 people, 23.08%
Asthma Aggravated: 3 people, 23.08%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 23.08%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Stable Angina (a constant chest pain): 1 person, 7.69%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 7.69%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Dizziness: 1 person, 7.69%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Artane and have Cardiac disorder?

- Check whether Cardiac disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Artane:

Artane (3,619 reports)

Cardiac disorder treatments and more:

Cardiac disorder (160,332 reports)

Browse all side effects of Artane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac disorder:

Cardiac disorder (2,041 drugs)

Browse all the conditions that are associated with Cardiac disorder:

Cardiac disorder (1,964 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trihexyphenidyl hydrochloride (the active ingredients of Artane) and Artane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.