Arthrotec and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Arthrotec (diclofenac sodium; misoprostol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tylenol W/ Codeine No. 4, and have Menopause.

The phase IV clinical study analyzes which people have Shock when taking Arthrotec. It is created by eHealthMe based on reports of 11,570 people who have side effects when taking Arthrotec from the FDA, and is updated regularly.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,213 drugs and 1,754 conditions by eHealthMe. Check the latest studies of Shock.



On Aug, 08, 2026

11,570 people reported to have side effects when taking Arthrotec.
Among them, 27 people (0.23%) have Shock.

Could Arthrotec cause Shock?

Among these 27 people:

How long have people been on Arthrotec when they have Shock? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Shock when taking Arthrotec? *

  • female: 48.15 %
  • male: 51.85 %

What is the age of people who have Shock when taking Arthrotec? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.85 %
  • 40-49: 7.69 %
  • 50-59: 19.23 %
  • 60+: 69.23 %

What are other drugs people take besides Arthrotec? *

  1. Provera: 7 people, 25.93%
  2. Vioxx: 7 people, 25.93%
  3. Celebrex: 7 people, 25.93%
  4. Daypro: 7 people, 25.93%
  5. Premarin: 7 people, 25.93%
  6. Tylenol W/ Codeine No. 4: 7 people, 25.93%
  7. Byetta: 4 people, 14.81%
  8. Hydrochlorothiazide: 4 people, 14.81%
  9. Lisinopril: 4 people, 14.81%
  10. Anaprox: 3 people, 11.11%

What are other side effects people have besides Shock? *

  1. Acute Kidney Failure: 10 people, 37.04%
  2. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 7 people, 25.93%
  3. Pulmonary Oedema (fluid accumulation in the lungs): 7 people, 25.93%
  4. Hypokalemia (low potassium): 7 people, 25.93%
  5. High Blood Pressure: 7 people, 25.93%
  6. Postoperative Ileus: 7 people, 25.93%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 25.93%
  8. Heart Attack: 7 people, 25.93%
  9. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 7 people, 25.93%
  10. Gastric Disorder (disease of stomach): 7 people, 25.93%

What are the existing conditions these people have? *

  1. Menopause (end of monthly cycles in women): 7 people, 25.93%
  2. Type 2 Diabetes: 3 people, 11.11%
  3. Insomnia (sleeplessness): 3 people, 11.11%
  4. Depression: 3 people, 11.11%
  5. Back Pain: 3 people, 11.11%
  6. Stable Angina (a constant chest pain): 2 people, 7.41%
  7. Constipation: 2 people, 7.41%
  8. Bipolar Disorder (mood disorder): 2 people, 7.41%
  9. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.70%
  10. Pneumonia: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Arthrotec and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arthrotec:

Shock treatments and more:

How severe was Shock and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac sodium; misoprostol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Browse all the conditions that are associated with Shock:

  • Shock (1,754 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium; misoprostol (the active ingredients of Arthrotec) and Arthrotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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