Aspirin and Angioedema - a phase IV clinical study of FDA data
Summary:
We study 590,931 people who have side effects when taking Aspirin. Angioedema is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Amlodipine and have Type 2 diabetes.
The phase IV clinical study analyzes which people take Aspirin and have Angioedema. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
590,931 people reported to have side effects when taking Aspirin.
Among them, 2,108 people (0.36%) have Angioedema.
What is Aspirin?
Aspirin has active ingredients of aspirin. It is used in blood clots. Currently, eHealthMe is studying from 600,540 Aspirin users.
What is Angioedema?
Angioedema (rapid swelling of the dermis) is found to be associated with 2,529 drugs and 1,999 conditions by eHealthMe. Currently, we are studying 42,647 people who have Angioedema.
Number of Aspirin and Angioedema reports submitted per year:

Time on Aspirin when people have Angioedema *:
Gender of people who have Angioedema when taking Aspirin*:
Age of people who have Angioedema when taking Aspirin *:
Common drugs people take besides Aspirin *:
Common side effects people have besides Angioedema *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Aspirin and have Angioedema?
Check whether Angioedema is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .
- Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Related studies
How severe was Angioedema and when was it recovered:
Expand to all the drugs that have ingredients of aspirin:
- Angioedema and drugs with ingredients of aspirin (3,397 reports)
Alternative drugs to, pros and cons of Aspirin:
- Aspirin (600,540 reports)
Browse all side effects of Aspirin:
a b c d e f g h i j k l m n o p q r s t u v w x y zAngioedema treatments and more:
- Angioedema (42,647 reports)
Common drugs associated with Angioedema:
- Lisinopril: 6,382 reports
- Ibu: 2,421 reports
- Ibuprofen: 2,420 reports
- Profen: 2,154 reports
- Aspirin: 2,108 reports
- Ramipril: 1,550 reports
- Amlodipine: 1,494 reports
- Xolair: 1,335 reports
- Metformin: 1,270 reports
- Acetylsalicylic acid: 1,206 reports
All the drugs that are associated with Angioedema:
- Angioedema (2,529 drugs)
Common conditions associated with Angioedema:
- High blood pressure: 9,457 reports
- Pain: 918 reports
- Rheumatoid arthritis: 694 reports
- Diabetes: 674 reports
- Asthma: 638 reports
- Type 2 diabetes: 608 reports
- High blood cholesterol: 583 reports
All the conditions that are associated with Angioedema:
- Angioedema (1,999 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on aspirin (the active ingredients of Aspirin) and Aspirin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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