Aspirin and Brain midline shift - a phase IV clinical study of FDA data

Summary:

Brain midline shift is reported as a side effect among people who take Aspirin (aspirin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pradaxa, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Brain midline shift when taking Aspirin. It is created by eHealthMe based on reports of 622,087 people who have side effects when taking Aspirin from the FDA, and is updated regularly.

What is Aspirin?

Aspirin has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 632,089 Aspirin users. Check the latest studies of Aspirin.

What is Brain midline shift?

Brain midline shift is found to be associated with 86 drugs and 214 conditions by eHealthMe. Check the latest studies of Brain midline shift.

On Aug, 12, 2026

622,087 people reported to have side effects when taking Aspirin.
Among them, 68 people (0.01%) have Brain midline shift.

Could Aspirin cause Brain midline shift?

Among these 68 people:

How long have people been on Aspirin when they have Brain midline shift? *

What is the gender of people who have Brain midline shift when taking Aspirin? *

female: 41.54 %
male: 58.46 %

What is the age of people who have Brain midline shift when taking Aspirin? *

What are other drugs people take besides Aspirin? *

What are other side effects people have besides Brain midline shift? *

Subdural Haematoma (blood collects between the skull and the surface of the brain): 31 people, 45.59%
Cerebral Haemorrhage (bleeding within the brain): 25 people, 36.76%
Fall: 17 people, 25.00%
Headache (pain in head): 16 people, 23.53%
Subarachnoid Haemorrhage (blood leaks into the space between two membranes that surround the brain): 13 people, 19.12%
Head Injury: 12 people, 17.65%
Haemorrhage Intracranial (bleeding within the skull): 12 people, 17.65%
Unresponsive To Stimuli: 11 people, 16.18%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 8 people, 11.76%
Speech Impairment (Adult) (inability to speak (adult)): 8 people, 11.76%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 24 people, 35.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 7 people, 10.29%
Nausea (feeling of having an urge to vomit): 6 people, 8.82%
Pain: 6 people, 8.82%
Depression: 5 people, 7.35%
Bipolar Disorder (mood disorder): 5 people, 7.35%
Mood Swings (an extreme or rapid change in mood): 4 people, 5.88%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 4 people, 5.88%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 4.41%
Asthma: 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Aspirin and have Brain midline shift?

- Check whether Brain midline shift is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aspirin:

Aspirin (632,089 reports)

Browse all side effects of Aspirin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain midline shift:

Brain midline shift (86 drugs)

Browse all the conditions that are associated with Brain midline shift:

Brain midline shift (214 conditions)

Related publications that referenced our studies

Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on aspirin (the active ingredients of Aspirin) and Aspirin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.