Atarax and Complex regional pain syndrome - a phase IV clinical study of FDA data

Summary:

Complex regional pain syndrome is reported as a side effect among people who take Atarax (hydroxyzine hydrochloride), especially for people who are female, 40-49 old, also take Premarin, and have Dermatitis allergic.

The phase IV clinical study analyzes which people have Complex regional pain syndrome when taking Atarax. It is created by eHealthMe based on reports of 22,841 people who have side effects when taking Atarax from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Complex regional pain syndrome?

Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)) is found to be associated with 332 drugs and 725 conditions by eHealthMe. Check the latest studies of Complex regional pain syndrome.

On Jul, 15, 2026

22,841 people reported to have side effects when taking Atarax.
Among them, 15 people (0.07%) have Complex regional pain syndrome.

Could Atarax cause Complex regional pain syndrome?

Among these 15 people:

What is the gender of people who have Complex regional pain syndrome when taking Atarax? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Complex regional pain syndrome when taking Atarax? *

What are other drugs people take besides Atarax? *

What are other side effects people have besides Complex regional pain syndrome? *

Oedema Peripheral (superficial swelling): 6 people, 40.00%
High Blood Pressure: 6 people, 40.00%
Headache (pain in head): 6 people, 40.00%
Allergic Rhinitis: 5 people, 33.33%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 33.33%
Dizziness: 5 people, 33.33%
Drowsiness: 5 people, 33.33%
Fall: 4 people, 26.67%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 26.67%
Oedema (fluid collection in tissue): 4 people, 26.67%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 2 people, 13.33%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 2 people, 13.33%
Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 1 person, 6.67%
Skin Exfoliation (removal of the oldest dead skin cells): 1 person, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Pain: 1 person, 6.67%
Neuralgia (pain in one or more nerves): 1 person, 6.67%
Nausea And Vomiting: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Atarax and have Complex regional pain syndrome?

- Check whether Complex regional pain syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atarax:

Atarax (23,553 reports)

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Complex regional pain syndrome:

Complex regional pain syndrome (332 drugs)

Browse all the conditions that are associated with Complex regional pain syndrome:

Complex regional pain syndrome (725 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Atarax) and Atarax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.