Atarax and Intervertebral disc degeneration - a phase IV clinical study of FDA data

Summary:

Intervertebral disc degeneration is reported as a side effect among people who take Atarax (hydroxyzine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Fosamax, and have Pain.

The phase IV clinical study analyzes which people have Intervertebral disc degeneration when taking Atarax. It is created by eHealthMe based on reports of 22,841 people who have side effects when taking Atarax from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Intervertebral disc degeneration?

Intervertebral disc degeneration (spinal disc degeneration) is found to be associated with 1,346 drugs and 1,481 conditions by eHealthMe. Check the latest studies of Intervertebral disc degeneration.

On Apr, 06, 2026

22,841 people reported to have side effects when taking Atarax.
Among them, 35 people (0.15%) have Intervertebral disc degeneration.

Could Atarax cause Intervertebral disc degeneration?

Among these 35 people:

How long have people been on Atarax when they have Intervertebral disc degeneration? *

What is the gender of people who have Intervertebral disc degeneration when taking Atarax? *

female: 79.41 %
male: 20.59 %

What is the age of people who have Intervertebral disc degeneration when taking Atarax? *

What are other drugs people take besides Atarax? *

What are other side effects people have besides Intervertebral disc degeneration? *

Back Pain: 25 people, 71.43%
Pain In Extremity: 22 people, 62.86%
Headache (pain in head): 21 people, 60.00%
Nausea (feeling of having an urge to vomit): 21 people, 60.00%
Weakness: 21 people, 60.00%
Anaemia (lack of blood): 20 people, 57.14%
Neuropathy Peripheral (surface nerve damage): 18 people, 51.43%
Osteomyelitis (infection of bone): 18 people, 51.43%
Purulent Discharge (discharge that contains pus): 17 people, 48.57%
Fever: 17 people, 48.57%

What are the existing conditions these people have? *

Pain: 13 people, 37.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 17.14%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 17.14%
Neuralgia (pain in one or more nerves): 5 people, 14.29%
Osteoporosis (bones weak and more likely to break): 4 people, 11.43%
Quit Smoking: 3 people, 8.57%
Depression: 3 people, 8.57%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 2 people, 5.71%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 5.71%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Atarax and have Intervertebral disc degeneration?

- Check whether Intervertebral disc degeneration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atarax:

Atarax (23,553 reports)

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,346 drugs)

Browse all the conditions that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,481 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Atarax) and Atarax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.