Micronor and Xyrem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micronor (norethindrone) and Xyrem (sodium oxybate). Common drug interactions include constipation among females.

The phase IV clinical study analyzes what interactions people have when they take Micronor and Xyrem. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Micronor?

Micronor has active ingredients of norethindrone. It is often used in birth control. eHealthMe is studying from 1,344 Micronor users. Check the latest studies of Micronor.

What is Xyrem?

Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.

On Jul, 11, 2026

26 people who take Micronor and Xyrem together, and have interactions are studied.

What are the common drug interactions of Micronor and Xyrem, by gender? *:

female:

Constipation
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)
Familial mediterranean fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash)
Haematuria (presence of blood in urine)
Overweight
Proteinuria (presence of protein in the urine)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Stent placement
Death

male:

n/a

What are the common drug interactions of Micronor and Xyrem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acne (skin problems that cause pimples)
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)
Constipation
Drug abuse
Drug abuser
Peripheral swelling
Weight increased
Familial mediterranean fever (genetic disease recurring attacks of abdominal pain, fever, pleurisy, arthritis, and rash)
Hysterectomy

40-49:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Back pain
Overweight
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Seasonal allergy (allergic condition due to certain season)
Breast cancer
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Cyst (a closed sac)
Hysterectomy

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 23.08%

* Approximation only. Some reports may have incomplete information.

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