Atorvastatin calcium and Neuroleptic malignant syndrome - a phase IV clinical study of FDA data

Summary:

Neuroleptic malignant syndrome is reported as a side effect among people who take Atorvastatin calcium (atorvastatin calcium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lorazepam, and have Depression.

The phase IV clinical study analyzes which people have Neuroleptic malignant syndrome when taking Atorvastatin calcium. It is created by eHealthMe based on reports of 72,753 people who have side effects when taking Atorvastatin calcium from the FDA, and is updated regularly.

What is Atorvastatin calcium?

Atorvastatin calcium has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 77,309 Atorvastatin calcium users. Check the latest studies of Atorvastatin calcium.

What is Neuroleptic malignant syndrome?

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents) is found to be associated with 551 drugs and 772 conditions by eHealthMe. Check the latest studies of Neuroleptic malignant syndrome.

On Jul, 19, 2026

72,753 people reported to have side effects when taking Atorvastatin calcium.
Among them, 34 people (0.05%) have Neuroleptic malignant syndrome.

Could Atorvastatin calcium cause Neuroleptic malignant syndrome?

Among these 34 people:

How long have people been on Atorvastatin calcium when they have Neuroleptic malignant syndrome? *

What is the gender of people who have Neuroleptic malignant syndrome when taking Atorvastatin calcium? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Neuroleptic malignant syndrome when taking Atorvastatin calcium? *

What are other drugs people take besides Atorvastatin calcium? *

Lorazepam: 14 people, 41.18%
Fluconazole: 12 people, 35.29%
Levothyroxine Sodium: 12 people, 35.29%
Omeprazole: 11 people, 32.35%
Sumatriptan Succinate: 10 people, 29.41%
Mometasone Furoate: 10 people, 29.41%
Risperidone: 10 people, 29.41%
Budesonide: 10 people, 29.41%
Furosemide: 10 people, 29.41%
Hydroxychloroquine Sulfate: 9 people, 26.47%

What are other side effects people have besides Neuroleptic malignant syndrome? *

Arrhythmias (irregular heartbeat): 12 people, 35.29%
Acute Kidney Failure: 9 people, 26.47%
Septic Shock (shock due to blood infection): 9 people, 26.47%
Fever: 8 people, 23.53%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 8 people, 23.53%
Electrolyte Imbalance: 7 people, 20.59%
Confusional State: 7 people, 20.59%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 6 people, 17.65%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 17.65%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 17.65%

What are the existing conditions these people have? *

Depression: 7 people, 20.59%
Agitation (state of anxiety or nervous excitement): 3 people, 8.82%
Psychotic Disorder: 2 people, 5.88%
Heart Attack: 2 people, 5.88%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 5.88%
Bipolar Disorder (mood disorder): 2 people, 5.88%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 2.94%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 1 person, 2.94%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 2.94%
Parkinson's Disease: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Atorvastatin calcium and have Neuroleptic malignant syndrome?

- Check whether Neuroleptic malignant syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atorvastatin calcium:

Atorvastatin calcium (77,309 reports)

Browse all side effects of Atorvastatin calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neuroleptic malignant syndrome:

Neuroleptic malignant syndrome (551 drugs)

Browse all the conditions that are associated with Neuroleptic malignant syndrome:

Neuroleptic malignant syndrome (772 conditions)

Related publications that referenced our studies

Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on atorvastatin calcium (the active ingredients of Atorvastatin calcium) and Atorvastatin calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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