Atra and Diarrhea - a phase IV clinical study of FDA data
Summary:
Diarrhea is reported as a side effect among people who take Atra (tretinoin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vesanoid, and have Acute myeloid leukaemia.
The phase IV clinical study analyzes which people have Diarrhea when taking Atra. It is created by eHealthMe based on reports of 483 people who have side effects when taking Atra from the FDA, and is updated regularly.
What is Atra?
Atra has active ingredients of tretinoin. eHealthMe is studying from 496 Atra users. Check the latest studies of Atra.
What is Diarrhea?
Diarrhea is found to be associated with 3,728 drugs and 5,753 conditions by eHealthMe. Check the latest studies of Diarrhea.
483 people reported to have side effects when taking Atra.
Among them, 12 people (2.48%) have Diarrhea.

Among these 12 people:
How long have people been on Atra when they have Diarrhea? *
- < 1 month: 80 %
- 1 - 6 months: 20 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Diarrhea when taking Atra? *
- female: 33.33 %
- male: 66.67 %
What is the age of people who have Diarrhea when taking Atra? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 11.11 %
- 20-29: 11.11 %
- 30-39: 11.11 %
- 40-49: 0.0 %
- 50-59: 33.33 %
- 60+: 33.33 %
What are other drugs people take besides Atra? *
- Amlodipine: 2 people, 16.67%
- Enbrel: 2 people, 16.67%
- Vesanoid: 2 people, 16.67%
- Zolpidem: 1 person, 8.33%
- Levofloxacin: 1 person, 8.33%
- Acanya: 1 person, 8.33%
- Carfilzomib: 1 person, 8.33%
- Clopidogrel: 1 person, 8.33%
- Creon: 1 person, 8.33%
- Fluconazole: 1 person, 8.33%
What are other side effects people have besides Diarrhea? *
- Nausea And Vomiting: 7 people, 58.33%
- Nausea (feeling of having an urge to vomit): 5 people, 41.67%
- Hepatotoxicity (chemical-driven liver damage): 3 people, 25.00%
- Oral Disorder (mouth disease): 3 people, 25.00%
- Fever: 3 people, 25.00%
- Dehydration (dryness resulting from the removal of water): 2 people, 16.67%
- Haemorrhage (bleeding): 2 people, 16.67%
- Weight Decreased: 2 people, 16.67%
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 2 people, 16.67%
- Cestode Infection (infection of the digestive tract by adult parasitic flatworms called cestodes or tapeworms): 2 people, 16.67%
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 33.33%
- Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 3 people, 25.00%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 16.67%
- Sleep Disorder: 1 person, 8.33%
- Pancreatic Carcinoma (pancreatic cancer): 1 person, 8.33%
- Pain: 1 person, 8.33%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 8.33%
- Acne (skin problems that cause pimples): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Atra and have Diarrhea?
- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Atra:
- Atra (496 reports)
Diarrhea treatments and more:
- Diarrhea (756,290 reports)
How severe was Diarrhea and when was it recovered:
Expand to all the drugs that have ingredients of tretinoin:
- Diarrhea and drugs with ingredients of tretinoin (524 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Atra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Diarrhea:
- Diarrhea (3,728 drugs)
Browse all the conditions that are associated with Diarrhea:
- Diarrhea (5,753 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tretinoin (the active ingredients of Atra) and Atra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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