Avalide and Herniated nucleus pulposus (slipped disk) - a phase IV clinical study of FDA data

Summary:

Herniated nucleus pulposus (slipped disk) is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are female, 60+ old, also take Lipitor, and have Pain.

The phase IV clinical study analyzes which people have Herniated nucleus pulposus (slipped disk) when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Herniated nucleus pulposus (slipped disk)?

Herniated nucleus pulposus (slipped disk) is found to be associated with 583 drugs and 909 conditions by eHealthMe. Check the latest studies of Herniated nucleus pulposus (slipped disk).

On Jul, 06, 2026

5,642 people reported to have side effects when taking Avalide.
Among them, 14 people (0.25%) have Herniated nucleus pulposus (slipped disk).

Could Avalide cause Herniated nucleus pulposus (slipped disk)?

Among these 14 people:

What is the gender of people who have Herniated nucleus pulposus (slipped disk) when taking Avalide? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Herniated nucleus pulposus (slipped disk) when taking Avalide? *

What are other drugs people take besides Avalide? *

What are other side effects people have besides Herniated nucleus pulposus (slipped disk)? *

Nausea (feeling of having an urge to vomit): 12 people, 85.71%
Stress And Anxiety: 12 people, 85.71%
Osteopenia (a condition where bone mineral density is lower than normal): 12 people, 85.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 85.71%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 12 people, 85.71%
Dyspnea (difficult or laboured breathing): 12 people, 85.71%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 12 people, 85.71%
Hypokalemia (low potassium): 12 people, 85.71%
Chest Pain: 12 people, 85.71%
Spinal Osteoarthritis (joint cartilage loss in spine): 12 people, 85.71%

What are the existing conditions these people have? *

Pain: 3 people, 21.43%
Stress And Anxiety: 2 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 14.29%
Depression: 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Cough: 1 person, 7.14%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 7.14%
Dyspnea (difficult or laboured breathing): 1 person, 7.14%
Dysmenorrhea (painful menstruation): 1 person, 7.14%
Dizziness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Herniated nucleus pulposus (slipped disk)?

- Check whether Herniated nucleus pulposus (slipped disk) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Herniated nucleus pulposus (slipped disk) treatments and more:

Herniated nucleus pulposus (slipped disk) (5,608 reports)

How severe was Herniated nucleus pulposus (slipped disk) and when was it recovered:

Herniated nucleus pulposus (slipped disk) in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Herniated nucleus pulposus (slipped disk) and drugs with ingredients of hydrochlorothiazide; irbesartan (14 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (583 drugs)

Browse all the conditions that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (909 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.